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Proteintech
NKD2 Polyclonal Antibody
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产品信息
16699-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
NKD2 Fusion Protein Ag10094 (1-311 aa encoded by BC012176)
偶联物
形式
Liquid
浓度
0.29 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MGKLQSKHA AAARKRRESP EGDSFVASAY ASGRKGAEEA ERRARDKQEL PNGDPKEGPF REDQCPLQVA LPAEKAEGRE HPGQLLSADD GERAANREGP RGPGGQRLNI DALQCDVSVE EDDRQEWTFT LYDFDNCGKV TREDMSSLMH TIYEVVDASV NHSSGSSKTL RVKLTVSPEP SSKRKEGPPA GQDREPTRCR MEGELAEEPR VADRRLSAHV RRPSTDPQPC SERGPYCVDE NTERRNHYLD LAGIENYTSR FGPGSQLCEK RSSAPRTHSG DKARGVGLCR ELWSQAGHPQ WPGPFPSGLV AV (1-311 aa encoded by BC012176)
靶标信息
Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity. Required for processing of TGFA and for targeting of TGFA to the basolateral membrane of polarized epithelial cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Dvl-binding protein NKD2; hNkd2; mNkd2; naked cuticle 1 homolog; naked cuticle 2 homolog; naked cuticle-2; Naked-2; Protein naked cuticle homolog 2
基因别名: 2210403L10Rik; AW212591; Naked2; NKD2
UniProt ID: (Human) Q969F2, (Mouse) Q8VE28
Entrez Gene ID: (Human) 85409, (Rat) 308068, (Mouse) 72293
exocytosis
positive regulation of protein processing
Wnt signaling pathway
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
Golgi vesicle fusion to target membrane
protein targeting to plasma membrane
positive regulation of establishment of protein localization to plasma membrane
negative regulation of canonical Wnt signaling pathway
transport
