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Invitrogen
NLRC4 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA1-4264
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic Peptide corresponding to the N-terminal sequence M N F I K D N S R A L I Q R M G M
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
PA1-4264 detects CLAN protein from human samples. This antibody detects both A and B isoforms.
PA1-4264 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~116 kDa protein representing CLAN-A and a ~43 kDa protein representing CLAN-B in lung lysate.
PA1-4264 immunizing peptide corresponds to N-terminal sequence M N F I K D N S R A L I Q R M G M.
Target Information
NLRC4 encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CARD, LRR, and NACHT-containing protein; Caspase recruitment domain-containing protein 12; CED-4-like protein Clan; Ice protease-activating factor; Ipaf; NLR family CARD domain-containing protein 4
Gene Aliases: CARD12; CLAN; CLAN1; IPAF; NLRC4; UNQ6189/PRO20215
Entrez Gene ID: (Human) 58484
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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