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Invitrogen
NMBR Polyclonal Antibody
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NMBR Antibody (PA5-98009) in WB
Western Blot analysis of NMBR using a NMBR Polyclonal antibody (Product # PA5-98009) at a concentration of 4.4 µg/mL. Positive WB detected in: A549 whole cell lysate, Hela whole cell lysate. A secondary Goat polyclonal antibody to rabbit IgG was applied at a 1:50,000 dilution. Observed band size: 44 kDa.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-98009
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human Neuromedin-B receptor protein (1-41AA)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
2.76 mg/mL
规格
100 µg
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
NMBR, also known as neuromedin B receptor, a Bombesin Receptor, activates phospholipase and protein kinase C and enhances calcium mobilization. It binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissues. Neuromedin B receptor expression has been reported in brain, particularly the olfactory bulb and thalamus, and in colon, liver, placenta, testis, spinal cord, and gastrointestinal tract. In addition, it has been shown to be present in cancer of the lung, ovary, and prostate. ESTs have been isolated from B-cell/lung/testis and brain libraries.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: bombesin receptor 1; epididymis secretory sperm binding protein Li 185a; Epididymis tissue protein Li 185a; Neuromedin-B receptor; Neuromedin-B-preferring bombesin receptor; NMB-R
基因别名: BB1; BB1R; BRS1; NMB-R; NMBR
Entrez Gene ID: (Human) 4829
G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
neuropeptide signaling pathway
bombesin receptor signaling pathway
negative regulation of interleukin-6 production
positive regulation of interferon-alpha production
positive regulation of osteoclast proliferation
antiviral innate immune response
sneeze reflex
positive regulation of respiratory gaseous exchange
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