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Invitrogen
NMDAR1 Polyclonal Antibody
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NMDAR1 Antibody (OPA1-04014) in WB
Western blot of NMDAR1 in HEK 293 cells (10 µg). Showing specific immunolabeling of a ~120 kDa band corresponding to NR1 subunit of the NMDAR1 polyclonal antibody (Product # OPA1-04014) receptor containing the C2 splice variant insert (lanes 3 and 4). No NR1 expression (lane 1); NR1 subunit containing only the C2 Insert (lane 2); NR1 subunit containing the C1 and C2 Insert (lane 3); NR1 subunit containing the N1 and C2 Insert (Lane 4).
产品信息
OPA1-04014
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acid residues specific to the NR1 subunit of rat GRIN1, C2' splice variant insert conjugated to KLH
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
This antibody is predicted to react with bovine and human based on 100% sequence homology.
In Western blot, this antibody detects an ~100 kDa protein representing the NR1 C2 splice variant from rat brain homogenate. It shows no cross-reactivity with the NR1 N1, C1, or C2 splice variants. Various bands of higher molecular weight have also been observed due to post-translational modifications.
Reconstitute with 50 µL of PBS.
靶标信息
NMDAR1 encodes a protein that is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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