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Invitrogen
NME5 Polyclonal Antibody
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NME5 Antibody (PA5-145411) in IHC (P)
Immunohistochemistry (Paraffin) analysis of NME5 in mouse testis tissue using NME5 Polyclonal Antibody (Product # PA5-145411) (20 µg/mL) and using PBS intead of the primary antibody as a control. The sample was then stained with HRP-Goat anti-Rabbit IgG polyclonal secondary antibody (2 µg/mL). DAB staining.
产品信息
PA5-145411
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Mouse NME5 protein, Leu16-Glu210 (Accession #Q99MH5)
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography, Protein A
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.05% Proclin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
For immunocytochemistry the cells were formalin fixed.
靶标信息
Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3'-5' exonuclease NME5; expressed in non-metastatic cells 5; NDK-H 5; NDP kinase homolog 5; nm23-M5; NME/NM23 family member 5; non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase); Nucleoside diphosphate kinase homolog 5; Rsph23
基因别名: 1700019D05Rik; Nm23-M5; Nme5
UniProt ID: (Mouse) Q99MH5
Entrez Gene ID: (Mouse) 75533, (Rat) 688903
response to reactive oxygen species
epithelial cilium movement
nucleoside diphosphate phosphorylation
GTP biosynthetic process
UTP biosynthetic process
CTP biosynthetic process
multicellular organism development
spermatogenesis
spermatid development
ventricular system development
cell differentiation
cilium assembly
spermatid differentiation
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
