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Invitrogen
NOLA1 Polyclonal Antibody
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产品信息
PA1-27677
产品规格
宿主/亚型
Chicken
/ IgY
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to human H/ACA ribonucleoprotein complex subunit 1.
偶联物
形式
Liquid
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
PA1-27677 detects NOLA1 from human and mouse samples.
PA1-27677 may be successfully used in Western blot applications. By Western blot, this antibody has only been tested on fusion protein.
The PA1-27720 immunogen is a synthetic peptide corresponding to human H/ACA ribonucleoprotein complex subunit 1.
靶标信息
Required for ribosome biogenesis and telomere maintenance. NOLA1 is part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. NOLA1 may also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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