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Proteintech
NONO Monoclonal Antibody (2A2B10)
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产品信息
66361-1-IG
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
2A2B10
抗原
NONO Fusion Protein Ag17609 (124-471 aa encoded by BC010049)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: IAKVELDNM PLRGKQLRVR FACHSASLTV RNLPQYVSNE LLEEAFSVFG QVERAVVIVD DRGRPSGKGI VEFSGKPAAR KALDRCSEGS FLLTTFPRPV TVEPMDQLDD EEGLPEKLVI KNQQFHKERE QPPRFAQPGS FEYEYAMRWK ALIEMEKQQQ DQVDRNIKEA REKLEMEMEA ARHEHQVMLM RQDLMRRQEE LRRMEELHNQ EVQKRKQLEL RQEEERRRRE EEMRRQQEEM MRRQQEGFKG TFPDAREQEI RMGQMAMGGA MGINNRGAMP PAPVPAGTPA PPGPATMMPD GTLGLTPPTT ERFGQAATME GIGAIGGTPP AFNRAAPGAE FAPNKRRRY (124-471 aa encoded by BC010049)
靶标信息
This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 54 kDa nuclear RNA- and DNA-binding protein; 55 kDa nuclear protein; DNA-binding p52/p100 complex, 52 kDa subunit; HGNC:7871; NMT-1; NMT55; non-POU domain-containing octamer (ATGCAAAT) binding protein; Non-POU domain-containing octamer-binding protein; non-POU-domain-containing; non-POU-domain-containing, octamer-binding protein; NonO protein; p54(nrb); protein phosphatase 1, regulatory subunit 114
基因别名: AA407051; AV149256; MRXS34; NMT55; nonA; NONO; NRB54; P54; P54NRB; PPP1R114
UniProt ID: (Human) Q15233, (Mouse) Q99K48, (Rat) Q5FVM4
Entrez Gene ID: (Human) 4841, (Mouse) 53610, (Rat) 317259
nucleotide binding
transcription regulatory region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
core promoter binding
chromatin binding
protein binding
identical protein binding
poly(A) RNA binding
nucleic acid binding
DNA binding
RNA binding
RNA metabolism protein
mRNA splicing, via spliceosome
DNA repair
DNA recombination
transcription, DNA-templated
regulation of transcription, DNA-templated
mRNA processing
circadian rhythm
RNA splicing
regulation of circadian rhythm
negative regulation of transcription, DNA-templated
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
cellular response to DNA damage stimulus
rhythmic process
