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Proteintech
NOX3 Polyclonal Antibody
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产品信息
30131-1-AP
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein
偶联物
形式
Liquid
纯化类型
Antigen affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: GRIVRGQTQD SLSLHNITFC RDRYAEWQTV AQCPVPQFSG KEPSAWKWIL GPVVLYACER IIRFWRFQQE VVITKVVSHP SGVLELHMKK RGFKMAPGQY ILVQCPAISS LEWHPFTLTS APQEDFFSVH IRAAGDWTAA LLEAFGAEGQ ALQEPWSLPR LAVDGPFGTA LTD
靶标信息
The NOX family of NAPDH oxidases is comprised of seven transmembrane proteins that oxidize intracellular NAPDH/NADH, causing electron transport across the membrane and the reduction of molecular oxygen to superoxide. NOX3 is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith. It has been suggested that NOX3 is activated by the Transient Receptor Potential Vanilloid 1 (TRPV1), and this activity causes increased levels of reactive oxygen species in the inner ear, which in turn leads to STAT1-mediated inflammation and hearing loss.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GP91-3; gp91phox homolog 3; head-tilt; Mitogenic oxidase 2; MOX-2; NADPH oxidase 3; NADPH oxidase catalytic subunit-like 3; NAPDH oxidase 3; NOX-3
基因别名: GP91-3; het; MOX-2; MOX2; nmf250; NOX3
UniProt ID: (Human) Q9HBY0, (Mouse) Q672J9
Entrez Gene ID: (Human) 50508, (Mouse) 224480
