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Abnova
NR2F1 Monoclonal Antibody (1A4)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00007025-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
1A4
抗原
NR2F1 (AAH04154.1, 141 a.a. approximately 240 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Tissue lysate).
Immunogen sequence: CRLKKCLKVG MRREAVQRGR MPPTQPNPGQ YALTNGDPLN GHCYLSGYIS LLLRAEPYPT SRYGSQCMQP NNIMGIENIC ELAARLLFSA VEWARNIPFF
靶标信息
The protein encoded by this gene is a nuclear hormone receptor and transcriptional regulator. The encoded protein acts as a homodimer and binds to 5'-AGGTCA-3' repeats. Defects in this gene are a cause of Bosch-Boonstra optic atrophy syndrome (BBOAS).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: chicken ovalbumin upstream promoter-transcription factor I; COUP transcription factor I; COUP-TF I; COUP-TF1; putative new variant 2; putative new variant 5; putative new variant 6; putative new variant 7; transcription factor COUP 1 (chicken ovalbumin upstream promoter 1, v-erb-a homolog-like 3); V-erbA-related protein 3
基因别名: BBOAS; BBSOAS; COUP-TFI; COUPTF1; EAR-3; EAR3; ERBAL3; SVP44; TCFCOUP1; TFCOUP1
UniProt ID: (Human) P10589
Entrez Gene ID: (Human) 7025
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
zinc ion binding
sequence-specific DNA binding
retinoic acid-responsive element binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
signal transduction
nervous system development
negative regulation of neuron projection development
cell differentiation
intracellular receptor signaling pathway
positive regulation of transcription from RNA polymerase II promoter
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
