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Invitrogen
NR5A2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-73018
产品规格
种属反应
Bovine,
Dog,
Chicken,
Horse,
Guinea pig,
Hamster,
Human,
Marsupial,
Mouse,
Non-human primate,
Pig,
Rabbit,
Rhesus monkey,
Rat,
Zebrafish
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A portion of amino acids 140-190 from human NR5A2.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.0 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Sequence homology: Orangutan, Chimpanzee, New World Monkey, Panda, Great Ape, Mole Rat, White cheeked gibbon, Platypus, Zebra finch, Catfish, Frog, Carolina anole (all 100%).
靶标信息
Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: b1-binding factor, hepatocyte transcription factor which activates enhancer II of hepatitis B virus; CYP7A promoter-binding factor; fetoprotein transcription factor; fetoprotein-alpha 1 (AFP) transcription factor; FTF; FTF/LRH-1; FTF; similar to nuclear hormone receptor; FTZ F1; FTZ F1beta; FTZ-F1 beta; FTZ-F1 beta2 protein; fushi tarazu; hB1F 2; hepatocytic transcription factor hB1F-3; live; liver receptor homolog 1; liver receptor homolog-1; nuclear receptor; Nuclear receptor subfamily 5 group A member 2; nuclear receptor subfamily 5, group A, member 2; nuclear receptor; similar to FTZ-F1; OR2.0; ORF; orphan nuclear receptor; steroidogenic factor 1; steroidogenic factor 2; unnamed protein product
基因别名: B1F; B1F2; CPF; D1Ertd308e; ff1a; FTF; ftz; FTZ-F1; FTZ-F1beta; ftzf1; hB1F-2; I79_021747; LRH-1; LRH1; mFTF; SF-2; sf1; UF2-H3B; zFF1; zFF1A; zFF1B
UniProt ID: (Chicken) O42101, (Human) O00482, (Mouse) P45448, (Rat) Q9QWM1, (Zebrafish) Q90YL6
transcription regulatory region sequence-specific DNA binding
chromatin binding
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
zinc ion binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription cofactor binding
DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
phospholipid binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
steroid hormone receptor activity
metal ion binding
C4 zinc finger nuclear receptor
hormone-mediated signaling pathway
tissue development
intracellular receptor signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
primary ovarian follicle growth
inner cell mass cell differentiation
positive regulation of T cell anergy
chromatin remodeling
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
spermatogenesis
bile acid metabolic process
embryo development ending in birth or egg hatching
neurogenesis
exocrine pancreas development
positive regulation of glucocorticoid biosynthetic process
negative regulation of chondrocyte differentiation
somatic stem cell population maintenance
embryonic cleavage
positive regulation of T cell proliferation
homeostatic process
positive regulation of viral genome replication
negative regulation of inflammatory response
positive regulation of T cell activation
Sertoli cell development
calcineurin-mediated signaling
morula formation
zygotic genome activation
positive regulation of stem cell differentiation
positive regulation of tendon cell differentiation
male gonad development
epithelial cell differentiation
regulation of cell proliferation
cholesterol homeostasis
cartilage development
pancreas morphogenesis
cellular response to leukemia inhibitory factor
liver development
digestive tract development
hepatoblast differentiation
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