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Invitrogen
NSA2 Polyclonal Antibody
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NSA2 Antibody (PA5-89854) in WB
Western blot analysis of NSA2 in extracts of various cell lines. Samples were incubated with NSA2 Polyclonal antibody (Product # PA5-89854) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
产品信息
PA5-89854
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human NSA2 (NP_0557011)
偶联物
形式
Liquid
浓度
1.59 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MPQNEYIELH RKRYGYRLDY HEKKRKKESR EAHERSKKAK KMIGLKAKLY HKQRHAEKIQ MKKTIKMHEK RNTKQKNDEK TPQGAVPAYL LDREGQSRAK VLSNMIKQKR KEKAGKWEVP LPKVRAQGET EVLKVIRTGK RKKKAWKRMV TKVCFVGDGF TRKPPKYERF IRPMGLRFKK AHVTHPELKA TFCLPILGVK KNPSSPLYTT LGVITKGTVI EVNVSELGLV TQGGKVIWGK YAQVTNNPEN DGCINAVLLV; Positive Samples: HeLa, 293T, Mouse heart, Mouse kidney, Mouse skeletal muscle, Rat heart, Rat kidney, Rat skeletal muscle; Cellular Location: Nucleus, nucleolus
靶标信息
This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ94393; Hairy cell leukemia protein 1; L-name related protein; L-name-related protein 42; LNR42; NSA2 ribosome biogenesis homolog; Ribosome biogenesis protein NSA2 homolog; TGF beta-inducible nuclear protein; TGF beta-inducible nuclear protein 1; TGF-beta inducible nuclear protein; TGF-beta-inducible nuclear protein 1; YR-29
基因别名: 5730427N09Rik; CDK105; HCL-G1; HCLG1; HUSSY-29; HUSSY29; LNR42; NSA2; Nsa2p; TINP1; Yr29
UniProt ID: (Human) O95478, (Mouse) Q9CR47
Entrez Gene ID: (Human) 10412, (Rat) 171456, (Mouse) 59050
