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Proteintech
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Immunogen sequence: FVTPHPRRIT PKFKSLSQTS SYNASMADSP GEESFEDLTE ESKTLAWNNI TKLQLHEHYK IHKEAVTGIT VSRNGSSVFT TSQDSTLKMF SKESKMLQRS ISFSNMALSS CLLLPGDATV ITSSWDNNVY FYSIAFGRRQ DTLMGHDDAV SKICWHDNRL YSASWDSTVK VWSGVPAEMP GTKRHHFDLL AELEHDVSVD TISLNAASTL LVSGTKEGTV NIWDLTTATL MHQIPCHSGI VCDTAFSPDS RHVLSTGTDG CLNVIDVQTG MLISSMTSDE PQRCFVWDGN SVLSGSQSGE LLVWDLLGAK ISERIQGHTG AVTCIWMNEQ CSSIITGGED RQIIFWKLQY
This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Factor associated with N-SMase activation; Factor associated with neutral sphingomyelinase activation; neutral sphingomyelinase (N-SMase) activation associated factor; Protein FAN
基因别名: FAN; GRAMD5; NSMAF
UniProt ID: (Human) Q92636
Entrez Gene ID: (Human) 8439