Proteintech

NSUN5 Polyclonal Antibody

11 篇参考文献
查看其他6个NSUN5抗体

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说明书
实验方案
问题与答案
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说明书
实验方案
问题与答案
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说明书
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问题与答案
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产品信息

15449-1-AP

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:500-1:1,000
查看6篇已发表文章 6篇已发表文章

免疫组化 (IHC)

-
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免疫组化（石蜡） (IHC (P))

1:20-1:200
-

免疫细胞化学 (ICC/IF)

1:10-1:100
查看3篇已发表文章 3篇已发表文章
产品规格

种属反应

Human, Mouse, Rat

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

NSUN5 Fusion Protein Ag7711 (117-466 aa encoded by BC008084)

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.21 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: RNEDLLEVG SRPGPASQLP RFVRVNTLKT CSDDVVDYFK RQGFSYQGRA SSLDDLRALK GKHFLLDPLM PELLVFPAQT DLHEHPLYRA GHLILQDRAS CLPAMLLDPP PGSHVIDACA APGNKTSHLA ALLKNQGKIF AFDLDAKRLA SMATLLARAG VSCCELAEED FLAVSPSDPR YHEVHYILLD PSCSGSGMPS RQLEEPGAGT PSPVRLHALA GFQQRALCHA LTFPSLQRLV YSTCSLCQEE NEDVVRDALQ QNPGAFRLAP ALPAWPHRGL STFPGAEHCL RASPETTLSS GFFVAVIERV EVPSSASQAK ASAPERTPSP APKRKKRQQR AAAGACTPPC T (117-466 aa encoded by BC008084)

靶标信息

NSUN5 is a member of the evolutionarily conserved NOL1/NOP2/Sun domain family. The encoded protein may function as a DNA methyltransferase in the nucleus. The gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: 28S rRNA (cytosine-C(5))-methyltransferase; FLJ10267; MGC986; NOL1-related protein; NOL1/NOP2/Sun domain family member 5; NOL1/NOP2/Sun domain family, member 5; NOL1R; NOP2/Sun domain family, member 5; NOP2/Sun domain family, member 5A; probable 28S rRNA (cytosine-C(5))-methyltransferase; putative methyltransferase NSUN5; Williams Beuren syndrome chromosome region 20A; Williams Beuren syndrome chromosome region 20A homolog; Williams-Beuren syndrome chromosomal region 20A protein; Williams-Beuren syndrome chromosomal region 20A protein homolog; Williams-Beuren syndrome critical region protein 20; Williams-Beuren syndrome critical region protein 20 copy A

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基因别名: 9830109N13Rik; AI326939; NOL1; NOL1R; NSUN5; NSUN5A; p120; p120(NOL1); RGD1309268; WBSCR20; WBSCR20A

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UniProt ID: (Human) Q96P11, (Mouse) Q8K4F6

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Entrez Gene ID: (Human) 55695, (Mouse) 100609, (Rat) 288595

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功能
RNA methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity poly(A) RNA binding rRNA (adenine-N6,N6-)-dimethyltransferase activity RNA binding protein C-terminal carboxyl O-methyltransferase activity tRNA (guanine-N2-)-methyltransferase activity methyltransferase activity C-methyltransferase activity N-methyltransferase activity O-methyltransferase activity S-methyltransferase activity mRNA methyltransferase activity tRNA methyltransferase activity protein methyltransferase activity 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity rRNA methyltransferase activity rRNA (uridine-2'-O-)-methyltransferase activity rRNA (adenine-N6-)-methyltransferase activity DNA-methyltransferase activity tRNA (guanine-N1-)-methyltransferase activity rRNA (cytosine-C5-)-methyltransferase activity selenocysteine methyltransferase activity arginine N-methyltransferase activity protein-arginine N-methyltransferase activity lysine N-methyltransferase activity protein-lysine N-methyltransferase activity tRNA (uracil) methyltransferase activity tRNA (guanine) methyltransferase activity tRNA (adenine) methyltransferase activity tRNA (cytosine) methyltransferase activity tRNA (cytosine-5-)-methyltransferase activity tRNA (adenine-N1-)-methyltransferase activity rRNA (adenine) methyltransferase activity rRNA (cytosine) methyltransferase activity rRNA (guanine) methyltransferase activity rRNA (uridine) methyltransferase activity transferase activity protein C-terminal leucine carboxyl O-methyltransferase activity 1-phenanthrol methyltransferase activity protein-arginine N5-methyltransferase activity methylarsonite methyltransferase activity dimethylarsinite methyltransferase activity 4,5-dihydroxybenzo(a)pyrene methyltransferase activity 1-hydroxypyrene methyltransferase activity 1-hydroxy-6-methoxypyrene methyltransferase activity demethylmenaquinone methyltransferase activity cobalt-precorrin-6B C5-methyltransferase activity cobalt-precorrin-7 C15-methyltransferase activity cobalt-precorrin-5B C1-methyltransferase activity cobalt-precorrin-3 C17-methyltransferase activity dimethylamine methyltransferase activity hydroxyneurosporene-O-methyltransferase activity tRNA (adenine-57, 58-N(1)-) methyltransferase activity methylamine-specific methylcobalamin:coenzyme M methyltransferase activity trimethylamine methyltransferase activity methanol-specific methylcobalamin:coenzyme M methyltransferase activity monomethylamine methyltransferase activity P-methyltransferase activity Se-methyltransferase activity 2-phytyl-1,4-naphthoquinone methyltransferase activity tRNA (uracil-2'-O-)-methyltransferase activity tRNA (cytosine-2'-O-)-methyltransferase activity phosphomethylethanolamine N-methyltransferase activity tRNA (cytosine-3-)-methyltransferase activity rRNA (cytosine-2'-O-)-methyltransferase activity rRNA (cytosine-N4-)-methyltransferase activity trihydroxyferuloyl spermidine O-methyltransferase activity
参与通路
rRNA processing biological_process methylation rRNA base methylation
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