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Proteintech
NUS1 Polyclonal Antibody
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产品信息
15986-1-AP
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
NUS1 Fusion Protein Ag8789 (1-293 aa encoded by BC013026)
偶联物
形式
Liquid
浓度
0.49 mg/mL
规格
73.5 µg
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MTGLYELVW RVLHALLCLH RTLTSWLRVR FGTWNWIWRR CCRAASAAVL APLGFTLRKP PAVGRNRRHH RHPRGGSCLA AAHHRMRWRA DGRSLEKLPV HMGLVITEVE QEPSFSDIAS LVVWCMAVGI SYISVYDHQG IFKRNNSRLM DEILKQQQEL LGLDCSKYSP EFANSNDKDD QVLNCHLAVK VLSPEDGKAD IVRAAQDFCQ LVAQKQKRPT DLDVDTLASL LSSNGCPDPD LVLKFGPVDS TLGFLPWHIR LTEIVSLPSH LNISYEDFFS ALRQYAACEQ RLGK (1-293 aa encoded by BC013026)
靶标信息
With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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