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Proteintech
NXF3 Polyclonal Antibody
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产品信息
13275-1-AP
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
NXF3 Fusion Protein Ag3998 (1-303 aa encoded by BC031616)
偶联物
形式
Liquid
浓度
0.46 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MSLPSGHTT GHTDQVVQRR ARCWDIYQRR FSSRSEPVNP GMHSSSHQQQ DGDAAMHGAH MDSPVRYTPY TISPYNRKGS FRKQDQTHVN MEREQKPPER RMEGNMPDGT LGSWFKITVP FGIKYNEKWL LNLIQNECSV PFVPVEFHYE NMHASFFVEN ASIAYALKNV SGKIWDEDNE KISIFVNPAG IPHFVHRELK SEKVEQIKLA MNQQCDVSQE ALDIQRLPFY PDMVNRDTKM ASNPRKCMAA SLDVHEENIP TVMSAGEMDK WKGIEPGEKC ADRSPVCTTF SDTSSNINSI LELF (1-303 aa encoded by BC031616)
靶标信息
This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Nuclear RNA export factor 3; TAP-like protein 3; TAPL-3
基因别名: Gm384; NXF3; TAPL3
UniProt ID: (Human) Q9H4D5
Entrez Gene ID: (Human) 56000, (Mouse) 245610
