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Invitrogen
Naxitamab Humanized Recombinant Human Monoclonal Antibody
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Naxitamab Humanized Antibody (MA5-42231) in SDS-PAGE
SDS-PAGE analysis of the recombinant Human Ganglioside GD2 protein expressed in CHO cells using a Naxitamab biosimilar monoclonal antibody (Product # MA5-42231). R denotes the lane was run under reducing conditions. NR denotes the lane was run under non-reducing conditions.
产品信息
MA5-42231
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG1, kappa
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
抗原
Human Ganglioside GD2
偶联物
形式
Liquid
浓度
3.45 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
靶标信息
Naxitamab is a humanized monoclonal antibody targeting the GD2 antigen. GD2 antigen is expressed on the surface of tumors generated by neuroectoderm, including neuroblastoma, melanoma and osteosarcoma. By binding to the GD2 antigen on the tumor surface, naxitamab can trigger antibody-mediated cytotoxicity and activate the complement system in the immune system to achieve the effect of killing tumors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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