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Invitrogen
Nebulin Monoclonal Antibody (NB2)
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产品信息
MA5-49308
产品规格
种属反应
Chicken
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
NB2
抗原
Chicken breast nebulin.
偶联物
形式
Lyophilized
浓度
Conc. Not Determined
保存液
ascites/1.2% sodium acetate with 2mg BSA
内含物
0.01mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Adding 1 mL of PBS buffer will yield a concentration of 100 µg/mL.
Positive Control - WB: Mouse Skeletal Muscle Tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
This gene encodes nebulin, a giant protein component of the cytoskeletal matrix that coexists with the thick and thin filaments within the sarcomeres of skeletal muscle. In most vertebrates, nebulin accounts for 3 to 4% of the total myofibrillar protein. The encoded protein contains approximately 30-amino acid long modules that can be classified into 7 types and other repeated modules. Protein isoform sizes vary from 600 to 800 kDa due to alternative splicing that is tissue-, species-, and developmental stage-specific. Of the 183 exons in the nebulin gene, at least 43 are alternatively spliced, although exons 143 and 144 are not found in the same transcript. Mutations in this gene are associated with recessive nemaline myopathy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp686C1456; FLJ11505; FLJ36536; FLJ39568; FLJ39584
