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NeoBiotechnologies
Neurofilament Recombinant Mouse Monoclonal Antibody (rNF421)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
4744-MSM5-P1
应用
建议稀释比
已发表文章
产品规格
种属反应
Chicken,
Human,
Mouse,
Pig,
Rat
宿主/亚型
Mouse
/ IgG1, kappa
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
rNF421
抗原
Recombinant full-length human NEFH protein
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
200 µg/mL
规格
100 µg
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 0.05% BSA
内含物
0.05% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
靶标信息
Involved in the maintenance of neuronal caliber, neurofilaments are the intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. NF-H has an important role in mature axons and is involved in amyotrophic lateral sclerosis (ALS).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 200 kDa neurofilament protein; heavy neurofilament polypeptide; heavy neurofilament subunit; high molecular weight neurofilament; hSTEp; NEF3; neurofilament; neurofilament 200kDa; neurofilament heavy polypeptide; Neurofilament triplet H protein; neurofilament, heavy polypeptide; neurofilament, heavy polypeptide 200kDa; NF 200 kD; NF-H; Nfh; NF200; NHC; unnamed protein product
基因别名: CMT2CC; mKIAA0845; NF-H; NF200; NFH
UniProt ID: (Human) P12036, (Mouse) P19246
Entrez Gene ID: (Human) 4744, (Pig) 100156492, (Chicken) 417020, (Mouse) 380684, (Rat) 24587
microtubule cytoskeleton organization
ovarian follicle atresia
axonogenesis
axon regeneration
neurofilament bundle assembly
intermediate filament cytoskeleton organization
intermediate filament bundle assembly
peripheral nervous system neuron axonogenesis
neurofilament cytoskeleton organization
axon development
postsynaptic modulation of chemical synaptic transmission
postsynaptic intermediate filament cytoskeleton organization
regulation of organelle transport along microtubule
response to sodium arsenite
cellular response to leukemia inhibitory factor
cell projection assembly
spinal cord development
hippocampus development
cerebral cortex development
neuron projection development
cellular response to oxidative stress
response to cocaine
cellular response to estradiol stimulus
cellular response to hydroperoxide
response to acrylamide
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
