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Invitrogen
Neurogenin 1 Polyclonal Antibody
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Product Details
PA5-72637
Product Specifications
Species Reactivity
Zebrafish
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 112-138 amino acids from the Central region of DANRE neurog1
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Neurogenin 1 is a basic helix-loop-helix (bHLH) proteins are transcription factors involved in determining cell type during development. NeuroG1 is a bHLH protein with dual cell-fate specification roles. It functions during neurogenesis, and it has also been shown to inhibit the differentiation of neural stem cells into astrocytes. NeuroG1 promotes neurogenesis by functioning as a transcriptional activator, yet it inhibits astrocyte differentiation by compartmentalizing the CREB-binding protein transcription complex away from astrocyte differentiation genes and by inhibiting STAT transcription factors essential for gliogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: basic helix-loop-helix transcription factor; NeuroD3; neurogenic differentiation 3; Neurogenic differentiation factor 3; Neurogenin-1; Neurogenin-related protein 1; NGN-1; transcription factor
Gene Aliases: cb260; chunp6899; neurod3; neurog1; NGN-1; ngn1; ngr1; Zath4c; zNgn1
UniProt ID: (Zebrafish) O42606
Entrez Gene ID: (Zebrafish) 30239
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
multicellular organism development
nervous system development
axonal fasciculation
peripheral nervous system development
dorsal spinal cord development
hindbrain morphogenesis
olfactory bulb development
forebrain neuron development
habenula development
neurogenesis
cell differentiation
neuron differentiation
axon regeneration
positive regulation of neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
generation of neurons
neuromast development
anterior lateral line nerve development
posterior lateral line nerve development
peripheral nervous system neuron development
negative regulation of neurogenesis
positive regulation of sequence-specific DNA binding transcription factor activity
olfactory placode development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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