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Invitrogen
Neutrophil elastase Polyclonal Antibody
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Neutrophil elastase Antibody (PA5-79198) in IHC (P)
Immunohistochemistry (Paraffin) analysis of Neutrophil elastase in paraffin-embedded section of mouse spleen tissue using Neutrophil elastase Polyclonal Antibody (Product # PA5-79198). Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. The tissue section was then incubated with the primary antibody at a 2 µg/... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-79198
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived mouse Elastase/ELANE/ELA2 recombinant protein (Position: S27-N265).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
500 µg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: mouse spleen tissue. IHC: mouse spleen tissue, rat spleen tissue.
靶标信息
The neutrophil form of elastase is 218 amino acids long, with two asparagine-linked carbohydrate chains (see glycosylation). It is present in azurophil granules in the neutrophil cytoplasm. There appear to be two forms of neutrophil elastase, termed IIa and IIb.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ELA2A; Elastase; elastase 2, neutrophil; Elastase-2; Elastase2; Leukocyte elastase; Neutrophil elastase; PE-1
基因别名: Ela2; Elane; F430011M15Rik; NE
UniProt ID: (Mouse) Q3UP87
Entrez Gene ID: (Rat) 299606, (Mouse) 50701
negative regulation of transcription from RNA polymerase II promoter
response to yeast
acute inflammatory response to antigenic stimulus
proteolysis
phagocytosis
biological_process
response to UV
response to lipopolysaccharide
defense response to bacterium
negative regulation of growth of symbiont in host
negative regulation of chemokine biosynthetic process
negative regulation of interleukin-8 biosynthetic process
positive regulation of interleukin-8 biosynthetic process
positive regulation of smooth muscle cell proliferation
positive regulation of immune response
defense response to fungus
leukocyte migration
neutrophil mediated killing of fungus
transcription from RNA polymerase II promoter
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
