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Invitrogen
Ninjurin 2 Polyclonal Antibody
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Product Details
PA5-66226
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Ninjurin 2. Recombinant protein control fragment (Product #RP-106906).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MAGLSRQLCAL SHPKKAAETQ TAEPGGAHAV CSRHPVRVKG LEGSEMESAR ENIDLQPGSS DPRSQPINLN
Highest antigen sequence identity to the following orthologs - mouse 28%, rat 32%.
Target Information
Ninjurin 2 (NINJ2) is a gene located on chromosome 12p13.2, encoding a member of the ninjurin family, which consists of cell surface proteins involved in promoting cell-cell adhesion and nerve regeneration. NINJ2 plays a pivotal role in neural repair processes, particularly in the peripheral nervous system, where it contributes to axonal growth and the formation of new neural connections following injury. This protein is expressed in various tissues, including the nervous system and endothelial cells, and is implicated in modulating inflammatory responses and cell-cell interactions. In addition to its role in the nervous system, NINJ2 is associated with vascular biology and immune cell migration, influencing processes such as angiogenesis and leukocyte transmigration. Altered expression or mutations in NINJ2 have been studied in the context of neurodegenerative diseases and stroke, where it may affect recovery and repair mechanisms. Research continues to explore NINJ2's potential as a therapeutic target for enhancing nerve regeneration and addressing vascular and inflammatory conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ56349; Nerve injury-induced protein 2; Ninjurin-2
Gene Aliases: NINJ2
UniProt ID: (Human) Q9NZG7
Entrez Gene ID: (Human) 4815
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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