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GenScript
Nivolumab Recombinant Rabbit Monoclonal Antibody (33H4), MonoRab™
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Nivolumab Antibody (A01987-40) in ELISA
MonoRab™ Anti-Niolumab Antibody (33H4), mAb, Rabbit (GenScript, A01987-40) blocks Niolumab binding with Human PD-1 recombinant protein (Z03370, PD-1 Fc Chimera, Human). Coating antigen: Niolumab, 1 µg/mL. PD-1-Fc-biotin final concentration: 10 ng/mL. MonoRab™ Anti-Niolumab Antibody (33H4), mAb, Rabbit (GenScript, A01987-40) dilutions start from 10 µg/mL. IC50 = 0.48 µg/mL.
产品信息
A01987-40
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
Mammalian cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
33H4
抗原
Nivolumab
偶联物
形式
Lyophilized
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/mL.
Nivolumab is a fully human monoclonal IgG4 antibody that is approved by the U.S. Food and Drug Administration for the treatment of bladder cancer. It binds to the programmed cell death protein 1 (PD-1) on the surface of activated T cells. Nivolumab functions as PD-1 inhibitor for targeted immunotherapy.GenScript MonoRab™ Anti-Nivolumab Antibody (33H4), mAb, Rabbit is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a rabbit immunized with Nivolumab.
Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below.
靶标信息
Nivolumab (Opdivo) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Nivolumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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