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Invitrogen
Norepinephrine Transporter Polyclonal Antibody
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Norepinephrine Transporter Antibody (PA5-89680) in WB
Western blot analysis of Norepinephrine Transporter in extracts of various cell lines. Samples were incubated with Norepinephrine Transporter Polyclonal antibody (Product # PA5-89680) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-89680
产品规格
种属反应
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein (or fragment).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
2.99 mg/mL
规格
299 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: A-549, SH-SY5Y, Mouse kidney, Mouse spinal cord; Cellular Location: Membrane, Multi-pass membrane protein
靶标信息
Norepinephrine Transporter [NET, or noradrenaline transporter (NAT)] is a monoamine transporter that transports the neurotransmitter noradrenaline from the synapse back to its vesicles for storage until later use. It also appears to transport the neurotransmitter dopamine in the same way, but to a lesser degree. Studies have shown a decrease in NET levels in the locus coeruleus in patients diagnosed with major depression. Cocaine, amphetamines and many therapeutic antidepressants, such as the SNRIs (serotonin-norepinephrine reuptake inhibitors) and the tricyclic antidepressants (TCAs) act to raise noradrenaline. Furthermore, deficits in the NET gene have been associated with ADHD.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: NaCl-dependent norepinephrine transporter; NE transporter; NET; neurotransmitter transporter, noradrenal; noradrenaline; Norepinephrine transporter; Sodium-dependent noradrenaline transporter; solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2; Solute carrier family 6 member 2; transmembrane region 4..26 transmembrane region 55..77 transmembrane region 105..123 transmembrane region 136..157
基因别名: NE-T; NET; Slc6a2; Slc6a5
UniProt ID: (Mouse) O55192
Entrez Gene ID: (Rat) 83511, (Mouse) 20538
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