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Invitrogen
Nortriptyline Polyclonal Antibody
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产品信息
PA1-75481
产品规格
种属反应
Chemical
宿主/亚型
Sheep
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Nortriptyline-BTG
偶联物
形式
Liquid
纯化类型
purified
保存液
PBS, pH 7.1
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Working Concentration: 5 µg/mL. Sensitivity: 10 ng/mL Nortriptyline produces 45% inhibition in a competitive ELISA employing Tricyclic Antidepressants (TCA) (4) polyclonal antibody.
靶标信息
Nortriptyline Base is a tricyclic antidepressant agent used for short-term treatment of various forms of depression. Nortriptyline blocks the norepinephrine presynaptic receptors, thereby blocking the reuptake of this neurotransmitter and raising the concentration in the synaptic cleft in the CNS. Nortriptyline also binds to alpha-adrenergic, histaminergic and cholinergic receptors. Long-term treatment with nortriptyline produces a downregulation of adrenergic receptors due to the increased stimulation of these receptors. [National Center for Biotechnology Information. PubChem Compound Database; CID=4543].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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