Invitrogen

Nuclear Pore Complex Monoclonal Antibody (39C7)

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

说明书
实验方案
问题与答案
技术支持
说明书
实验方案
问题与答案
技术支持
说明书
实验方案
问题与答案
技术支持

产品信息

MA5-33097

应用
建议稀释比
已发表文章

免疫细胞化学 (ICC/IF)

1:50-1:100
-
产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

39C7

抗原

Yeast nuclear preparations

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.25 mg/mL

保存液

tissue culture supernatant

内含物

10mM sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2802647

靶标信息

The nuclear pore complex (NPC) serves as the sole bidirectional gateway of macromolecules in and out of the nucleus. Each NPC consists of ~1,000 protein subunits, termed nucleoporins, and totals to a molecular mass of ~110 Mda. NPCs maintain the integrity of the nuclear compartment by preventing macromolecules from freely diffusing in or out of the nucleus. (Annu Rev Biochem, 2019. PMID 30883195)

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
引用该产品

生物信息学

蛋白别名: 107 kDa nucleoporin; 133 kDa nucleoporin; 153 kDa nucleoporin; 155 kDa nucleoporin; 160 kDa nucleoporin; 205 kDa nucleoporin; 214 kDa nucleoporin; 35 kDa nucleoporin; 50 kDa nucleoporin; 62 kDa nucleoporin; 85 kDa nucleoporin; 88 kDa nuclear pore complex protein; 88 kDa nucleoporin; 93 kDa nucleoporin; 98 kDa nucleoporin; CAN protein, putative oncogene; CBP-interacting protein 4; FROUNT; Gene trap locus 1-13 protein; gene trap locus-13; GLFG-repeat containing nucleoporin; GTL-13; karyoporin; Mitotic phosphoprotein 44; MP-44; Nuclear envelope pore membrane protein POM 210; nuclear pore associated protein 60 kDa; nuclear pore complex 1; nuclear pore complex protein 88; nuclear pore complex protein hnup153; Nuclear pore complex protein Nup107; Nuclear pore complex protein Nup133; Nuclear pore complex protein Nup153; Nuclear pore complex protein Nup155; Nuclear pore complex protein Nup160; Nuclear pore complex protein Nup205; Nuclear pore complex protein Nup214; Nuclear pore complex protein Nup50; Nuclear pore complex protein Nup53; Nuclear pore complex protein Nup85; Nuclear pore complex protein Nup88; Nuclear pore complex protein Nup93; nuclear pore complex protein Nup98; Nuclear pore complex protein Nup98-Nup96; nuclear pore glycoprotein 62; Nuclear pore glycoprotein p62; Nuclear pore membrane glycoprotein 210; nuclear pore membrane protein 210; Nuclear pore protein gp210; Nuclear pore-associated protein 60 kDa-like; nuclear pore-associated protein 60L; nucleoporin 107kDa; nucleoporin 133; nucleoporin 133kD; nucleoporin 133kDa; nucleoporin 153kD; nucleoporin 153kDa; nucleoporin 155kD; nucleoporin 155kDa; nucleoporin 160kD; nucleoporin 160kDa; nucleoporin 205kDa; nucleoporin 210; nuclear pore membrane glycoprotein 210; nuclear pore membrane protein 210; nucleoporin 210kDa; nucleoporin 214kDa; nucleoporin 35kDa; nucleoporin 50 kDa; nucleoporin 50kD; nucleoporin 50kDa; nucleoporin 62kD; nucleoporin 62kDa; nucleoporin 85kDa; nucleoporin 88kDa; nucleoporin 93kDa; nucleoporin 98kD; nucleoporin 98kDa; Nucleoporin Nup107; Nucleoporin Nup133; Nucleoporin Nup153; Nucleoporin Nup155; Nucleoporin Nup160; Nucleoporin Nup205; Nucleoporin Nup210; Nucleoporin Nup214; Nucleoporin NUP35; Nucleoporin Nup50; Nucleoporin NUP53; Nucleoporin Nup62; Nucleoporin Nup75; Nucleoporin Nup84; Nucleoporin Nup85; Nucleoporin Nup88; Nucleoporin Nup93; nucleoporin Nup98; nucleoprotein 50; Nucleoprotein 50kD; Nup98-Nup96; NUP98/PHF23 fusion 2 protein; p105; P140; pericentrin 1; Pericentrin-1; POM210; Pore membrane protein of 210 kDa; preimplantation protein 2; Protein CAN

查看更多 收起

基因别名: 160kDa; 1700030K07Rik; 2310006I24Rik; 2410008G02Rik; 2810011M03Rik; 35kDa; 3830404O05Rik; 4732457F17; 5330402E05Rik; 9830001L10; AA414952; AA589433; ADAR2; ADIR2; AI413123; AI426861; AI790512; AI836801; AI849286; ATFB15; AU020188; AU045898; AV248391; AW541137; B130015D15Rik; BC039282; C76801; C7orf14; C88147; CAIN; CAN; Cip4; D2H9S46E; D7Ertd649e; D930027M19Rik; FROUNT; gp190; GP210; Gtl-13; Gtl1-13; Gtl13; hNUP133; HNUP153; IBSN; KIAA0023; KIAA0095; KIAA0197; KIAA0225; KIAA0791; KIAA0906; mermaid; mKIAA0197; mKIAA0225; mKIAA0791; MP-44; MP44; N153; N155; NIC96; NO44; NP44; Np62; NPAP60; NPAP60L; NPHS11; NPHS12; NPHS13; NUCZINK; NUP107; NUP120; NUP133; NUP153; NUP155; NUP160; NUP196; NUP205; NUP210; NUP214; NUP35; NUP50; NUP53; NUP62; NUP75; NUP84; NUP85; NUP88; NUP93; NUP96; NUP98; Nupc1; p62; PCNT1; POM210; Prei2; PRO1146; PSEC0245; RGD1304977; Rtp60; SNDI

查看更多 收起

UniProt ID: (Human) P57740, (Human) Q8WUM0, (Human) P49790, (Human) O75694, (Human) Q12769, (Human) Q92621, (Human) Q8TEM1, (Human) P35658, (Human) Q8NFH5, (Human) Q9UKX7, (Human) P37198, (Human) Q9BW27, (Human) Q99567, (Human) Q8N1F7, (Human) P52948, (Rat) O08587, (Mouse) Q8BH74, (Mouse) Q8R0G9, (Rat) P37199, (Mouse) Q99P88, (Mouse) Q9Z0W3, (Rat) P11654, (Mouse) Q9QY81, (Mouse) Q80U93, (Rat) Q68FY1, (Mouse) Q8R4R6, (Mouse) Q9JIH2, (Rat) P17955, (Mouse) Q63850, (Rat) Q4QQS8, (Mouse) Q8R480, (Mouse) Q8CEC0, (Rat) O08658, (Mouse) Q8BJ71, (Rat) Q66HC5, (Mouse) Q6PFD9, (Rat) P49793

查看更多 收起

Entrez Gene ID: (Human) 57122, (Human) 55746, (Human) 9972, (Human) 9631, (Human) 23279, (Human) 23165, (Human) 23225, (Human) 8021, (Human) 129401, (Human) 10762, (Human) 23636, (Human) 79902, (Human) 4927, (Human) 9688, (Human) 4928, (Rat) 25497, (Rat) 116555, (Mouse) 103468, (Mouse) 234865, (Rat) 292085, (Rat) 25281, (Mouse) 218210, (Rat) 117021, (Mouse) 170762, (Mouse) 59015, (Rat) 311182, (Mouse) 70699, (Rat) 362335, (Rat) 58958, (Mouse) 54563, (Mouse) 227720, (Rat) 296634, (Rat) 295692, (Mouse) 69482, (Mouse) 18141, (Rat) 65274, (Mouse) 18226, (Rat) 287830, (Mouse) 445007, (Mouse) 19069, (Rat) 113929, (Mouse) 71805, (Rat) 291874, (Mouse) 269966, (Rat) 81738

查看更多 收起

功能
nucleocytoplasmic transporter activity protein binding structural constituent of nuclear pore chromatin binding double-stranded DNA binding nuclear localization sequence binding zinc ion binding Ran GTPase binding identical protein binding protein anchor transporter activity protein dimerization activity nuclear export signal receptor activity nucleotide binding single-stranded DNA binding phospholipid binding kinesin binding receptor signaling complex scaffold activity Hsp70 protein binding SH2 domain binding ubiquitin binding thyroid hormone receptor binding PTB domain binding Hsp90 protein binding RNA binding porin activity DNA binding protein homodimerization activity CCR2 chemokine receptor binding peptide binding transporter scaffold/adaptor protein structural protein
参与通路
posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery regulation of transcription, DNA-templated mRNA export from nucleus tRNA export from nucleus protein import into nucleus sister chromatid cohesion mitotic nuclear envelope disassembly regulation of glucose transport viral process protein sumoylation viral transcription gene silencing by RNA nuclear pore complex assembly intracellular transport of virus regulation of cellular response to heat transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery chromatin organization nuclear pore organization neural tube development neurogenesis nuclear pore distribution paraxial mesoderm development somite development mitotic nuclear division viral entry into host cell negative regulation of RNA export from nucleus viral penetration into host nucleus RNA export from nucleus nuclear envelope organization protein targeting to nuclear inner membrane atrial cardiac muscle cell action potential protein transport protein import into nucleus, docking nucleocytoplasmic transport protein export from nucleus regulation of mRNA stability regulation of cell cycle NLS-bearing protein import into nucleus transmembrane transport transcription, DNA-templated cell surface receptor signaling pathway spermatogenesis cell aging cell death negative regulation of cell proliferation hormone-mediated signaling pathway regulation of signal transduction negative regulation of epidermal growth factor receptor signaling pathway regulation of protein import into nucleus negative regulation of apoptotic process negative regulation of programmed cell death positive regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of MAP kinase activity positive regulation of epidermal growth factor receptor signaling pathway positive regulation of transcription, DNA-templated regulation of Ras protein signal transduction negative regulation of Ras protein signal transduction protein heterotrimerization ribonucleoprotein complex export from nucleus lamellipodium assembly macrophage chemotaxis ribosomal large subunit export from nucleus ribosomal small subunit export from nucleus positive regulation of defense response to virus by host poly(A)+ mRNA export from nucleus positive regulation of SMAD protein import into nucleus SMAD protein signal transduction renal system development glomerular visceral epithelial cell development glomerular visceral epithelial cell migration mitophagy in response to mitochondrial depolarization xenophagy negative regulation of hydrogen peroxide-induced cell death DNA replication telomere tethering at nuclear periphery neural tube formation intracellular transport mRNA transport transport biological_process cell migration chemotaxis cytokine-mediated signaling pathway
guarantee_icon

性能保障

只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符，您即可享受免费退换货服务。*

了解更多
help_icon

随时为您服务

获取常见问题的专家解答，或者直接联系我们的技术专家，咨询应用、设备、常规产品使用问题。

联系技术支持