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Invitrogen
OAZ1 Polyclonal Antibody
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OAZ1 Antibody (PA5-14385) in IHC (P)
Immunohistochemistry analysis of OAZ1 in formalin-fixed and paraffin-embedded mouse heart tissue. Samples were incubated with OAZ1 polyclonal antibody (Product # PA5-14385) which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-14385
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 2-31 amino acids from the N-terminal region of human OAZ1
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
2 mg/mL
规格
800 µg
纯化类型
Ammonium sulfate precipitation, Size-exclusion - Dialysis
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
OAZ1 catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. This protein play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. The protein expression is auto-regulated by polyamine-enhanced translational frameshifting.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: antizyme 1; AZ1; ODC-Az; Ornithine decarboxylase antizyme 1
基因别名: Antizyme; AZ-1; AZ1; OAZ; OAZ1; ODC-Az; ODCAC
UniProt ID: (Mouse) P54369, (Rat) P54370
Entrez Gene ID: (Mouse) 18245, (Rat) 25502
polyamine metabolic process
polyamine biosynthetic process
transport
negative regulation of catalytic activity
positive regulation of protein catabolic process
positive regulation of intracellular protein transport
negative regulation of polyamine transmembrane transport
negative regulation of protein homodimerization activity
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