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Proteintech
OCT2 Polyclonal Antibody
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产品信息
10867-2-AP
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
OCT2 Fusion Protein Ag0955 (100-400 aa encoded by BC006101)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: AGDIQQLLQ LQQLVLVPGH HLQPPAQFLL PQAQQSQPGL LPTPNLFQLP QQTQGALLTS QPRAGLPTQP PKCLEPPSHP EEPSDLEELE QFARTFKQRR IKLGFTQGDV GLAMGKLYGN DFSQTTISRF EALNLSFKNM CKLKPLLEKW LNDAETMSVD SSLPSPNQLS SPSLGFDGLP GRRRKKRTSI ETNVRFALEK SFLANQKPTS EEILLIAEQL HMEKEVIRVW FCNRRQKEKR INPCSAAPML PSPGKPASYS PHMVTPQGGA GTLPLSQASS SLSTTAQTPA LKAATRLSAC QA (100-400 aa encoded by BC006101)
靶标信息
OCT-2 is a transcription factor belonging to the POU homeo-domain family that binds to the Ig gene octamer sites regulating B cell specific genes. OCT-2 protein expression is not restricted to B cells, although expression levels are much higher in these cells. OCT-2 expression is reported to be significantly greater in germinal center derived lymphomas, although other B cell lymphomas also display high levels of expression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: homeobox protein; Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; Oct-2; Octamer-binding protein 2; Octamer-binding transcription factor 2; OTF-2; POU domain, class 2, transcription factor 2
基因别名: Oct-2; OCT2; Oct2a; Oct2b; Otf-2; OTF2; POU2F2
UniProt ID: (Human) P09086, (Mouse) Q00196
Entrez Gene ID: (Human) 5452, (Mouse) 18987
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein domain specific binding
sequence-specific DNA binding
DNA binding
mature B cell differentiation
immunoglobulin secretion involved in immune response
transcription from RNA polymerase II promoter
humoral immune response
snRNA transcription from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase II promoter
cell maturation
transcription, DNA-templated
regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
immunoglobulin secretion
