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Proteintech
OGDH Recombinant Rabbit Monoclonal Antibody (1C16)
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产品信息
82773-1-RR
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
1C16
抗原
OGDH fusion protein Ag7368
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.7 mg/mL
规格
70 µg
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: SGQDVERGTF SHRHHVLHDQ NVDKRTCIPM NHLWPNQAPY TVCNSSLSEY GVLGFELGFA MASPNALVLW EAQFGDFHNT AQCIIDQFIC PGQAKWVRQN GIVLLLPHGM EGMGPEHSSA RPERFLQMCN DDPDVLPDLK EANFDINQLY DCNWVVVNCS TPGNFFHVLR RQILLPFRKP LIIFTPKSLL RHPEARSSFD EMLPGTHFQR VIPEDGPAAQ NPENVKRLLF CTGKVYYDLT RERKARDMVG QVAITRIEQL SPFPFDLLLK EVQKYPNAEL AWCQEEHKNQ GYYDYVKPRL RTTISRAKPV WYAGRDPAAA PATGNKKTHL TELQRLLDTA FDLDVFKNFS
靶标信息
This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitocondrial matrix and uses thiamine pyrophosphate as a cofactor. A congential deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 2-oxoglutarate dehydrogenase complex component E1; 2-oxoglutarate dehydrogenase E1 component, mitochondrial; 2-oxoglutarate dehydrogenase, mitochondrial; Alpha-ketoglutarate dehydrogenase; Alpha-KGDH-E1; E1o; OGDC-E1; oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide); oxoglutarate decarboxylase; oxoglutarate dehydrogenase (lipoamide); oxoglutarate dehydrogenase (succinyl-transferring); testicular tissue protein Li 131; Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase; unnamed protein product
基因别名: 2210403E04Rik; 2210412K19Rik; AA409584; AKGDH; d1401; E1k; E1o; HsOGDH; KGD1; Kiaa4192; mKIAA4192; OGDC; OGDH; OGDH-E1; OGDH2; OGDHD; Ogdhl
UniProt ID: (Human) Q02218, (Mouse) Q60597, (Rat) Q5XI78
Entrez Gene ID: (Human) 4967, (Mouse) 18293, (Rat) 360975
oxoglutarate dehydrogenase (succinyl-transferring) activity
protein binding
oxidoreductase activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
oxidoreductase activity, acting on the aldehyde or oxo group of donors
thiamine pyrophosphate binding
heat shock protein binding
metal ion binding
chaperone binding
oxoglutarate dehydrogenase (NAD+) activity
dehydrogenase
generation of precursor metabolites and energy
glycolytic process
tricarboxylic acid cycle
2-oxoglutarate metabolic process
succinyl-CoA metabolic process
NAD metabolic process
cerebellar cortex development
striatum development
hippocampus development
thalamus development
pyramidal neuron development
tangential migration from the subventricular zone to the olfactory bulb
olfactory bulb mitral cell layer development
NADH metabolic process
metabolic process
oxidation-reduction process
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