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Invitrogen
ONECUT2 Monoclonal Antibody (606014)
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ONECUT2 Antibody (MA5-24275) in ICC/IF
Immunocytochemistry analysis of ONECUT2 was detected in immersion fixed HepG2 human hepatocellular carcinoma cell line. The cells were labeled with ONECUT2 Mouse Monoclonal Antibody (Product # MA5-24275) using a dilution of 10 µg/mL for 3 hours at room temperature. Cells were stained using the Northern-Lights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red) counterstained with DAPI (blue). Specific staining was localized to nuclei.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-24275
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
606014
抗原
E. coli-derived recombinant human ONECUT2/OC-2 Gln185-Thr326
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A/G
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
No cross-reactivity with recombinant human ONECUT is observed.
Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.
靶标信息
ONECUT2 is a member of the transcription factors of the ONECUT class, whose prototype is hepatocyte nuclear factor (HNF)-6. The distribution of OC-2 mRNA in humans is tissue-restricted, the strongest expression being detected in the liver and skin. ONECUT2 participates in the network of transcription factors required for liver differentiation and metabolism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hepatocyte nuclear factor 6-beta; HNF-6-beta; HNF-6B; onecut 2; ONECUT-2 homeodomain transcription factor; transcription factor ONECUT-2
基因别名: OC-2; OC2
UniProt ID: (Human) O95948
Entrez Gene ID: (Human) 9480
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
sequence-specific double-stranded DNA binding
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