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Invitrogen
OPRK1 Polyclonal Antibody
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产品信息
OPA1-03101
应用
建议稀释比
已发表文章
产品规格
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide derived from the internal region of the mouse k-opioid receptor.
偶联物
形式
Liquid
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
OPA1-03101 detects kappa opioid receptor from mouse and rat tissues. Human kappa opioid receptor has not been tested, but is expected to react based on 93% sequence homology.
OPA1-03101 has been successfully used in Western blot procedures. Suggested positive control is rat brain extract.
OPA1-03101 is a sythetic peptide derived from the internal region of the mouse kappa-opioid receptor.
靶标信息
This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
