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Proteintech
ORM2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
11199-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ORM2 Fusion Protein Ag1667 (1-201 aa encoded by BC015964)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.45 mg/mL
规格
67.5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody can recognize both ORM1 and ORM2.
Immunogen sequence: MALSWVLTV LSLLPLLEAQ IPLCANLVPV PITNATLDRI TGKWFYIASA FRNEEYNKSV QEIQATFFYF TPNKTEDTIF LREYQTRQNQ CFYNSSYLNV QRENGTVSRY EGGREHVAHL LFLRDTKTLM FGSYLDDEKN WGLSFYADKP ETTKEQLGEF YEALDCLCIP RSDVMYTDWK KDKCEPLEKQ HEKERKQEEG ES (1-201 aa encoded by BC015964)
靶标信息
AGP (a 1-acid Glycoprotein) is an acute phase plasma protein synthesized by the liver. It functions to regulate the interaction between blood cells and endothelial cells, and together with haptoglobin and C reactive protein, it also mediates the extravasation of cells during infection and inflammation. Expression of AGP is induced by acute-phase stimulatory agents such as bacterial lipopolysaccharides. AGP has a high affinity, low capacity binding for basic drugs at physiological pH. In human plasma, AGP is found at levels of 0.5-1.4 mg/mL, though this is elevated during acute inflammation, and, as a result, levels of this protein can be used to diagnose inflammatory conditions. Multiple AGP genes exist, including AGP-1, AGP-2, AGP-3 and AGP-8. AGP-1 and AGP-2 contain five and six potential N-glycosylation sites, respectively. Abnormal expression of the APG-1 gene is linked to sarcoidosis and other immunogenetic diseases, while mutations in the APG-2 gene are associated with different types of carcinomas.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: AGP 2; alpha-1-acid glycoprotein; alpha-1-acid glycoprotein, type 2; bM340H1.5 (orosomucoid 2); OMD 2; OMD2; ORM2; Orosomucoid2; unnamed protein product
基因别名: AGP-B; AGP-B'; Agp1; AGP2; Orm-2
UniProt ID: (Human) P19652, (Mouse) P07361
Entrez Gene ID: (Human) 5005, (Mouse) 18406
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
