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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total OSBPL2.
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ20223; MGC4307; MGC8342; ORP-2; OSBP-related protein 2; oxysterol-binding protein-like 2; Oxysterol-binding protein-related protein 2; RP11-157P1.2
基因别名: C130070J12Rik; KIAA0772; mKIAA0772; ORP-2; ORP2; OSBPL2
UniProt ID: (Mouse) Q8BX94
Entrez Gene ID: (Mouse) 228983