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Invitrogen
OTOF Polyclonal Antibody
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产品信息
PA5-52445
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human OTOF
偶联物
形式
Liquid
浓度
0.2 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: WWSKYFASID TMKEQLRQQE PSGIDLEEKE EVDNTEGLKG SMKGKEKARA AKEEKKKKTQ SSGSGQGSEA PEKKKPKIDE LKVYPKELES EFDNFEDWLH TFNLLRGKTG DDE
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 88%.
靶标信息
Otoferlin is a protein that in humans is encoded by the OTOF gene. Mutations in this gene are a cause of neurosensory nonsyndromic recessive deafness, DFNB9. The short form of the encoded protein has three C2 domains, a single carboxy-terminal transmembrane domain found also in the C. elegans spermatogenesis factor FER-1 and human dysferlin, while the long form has six C2 domains. The homology suggests that this protein may be involved in vesicle membrane fusion. Several transcript variants encoding multipleisoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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