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GenScript
Ocrelizumab Recombinant Rabbit Monoclonal Antibody (15E7), MonoRab™
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Ocrelizumab Antibody (A02259-40) in ELISA
Standard curve of Ocrelizumab sandwich ELISA by A02258 (12G10) and A02259 (15E7). In this ELISA assay, MonoRab™ Anti-Ocrelizumab Antibody (12G10), mAb, Rabbit (GenScript, A02258) was coated at a concentration of 1 μg/mL, and MonoRab™ Anti-Ocrelizumab Antibody (15E7), mAb, Rabbit (GenScript, A02259) conjugated with Biotin was used as a detection antibody at a concentration of 0.5 μg/mL. In this ELISA assay, a four-parameter logistic curve fitting program was used to create a standard curve with the R-Square equal to 0.99978. The typical dyn... View More
产品信息
A02259-40
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG, kappa
Expression System
Mammalian cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
15E7
抗原
Ocrelizumab
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.2
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/mL.
Sandwich ELISA recommended dilution: 0.5-2 µg/mL; Competitive ELISA recommended dilution: 1-10 µg/mL
The lyophilized product remains stable up to 1 year at -20 °C from date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid repeated freezing and thawing cycles.
靶标信息
Ocrelizumab is a CD20-directed cytolytic antibody indicated for the treatment of patients with relapsing or primary progressive forms of multiple sclerosis. It is a second-generation recombinant humanized monoclonal IgG1 antibody that selectively targets the B lymphocytes that express the CD20 antigen. As a humanized molecule, ocrelizumab is expected to be less immunogenic with repeated infusions which improves the benefit-to-risk profile for patients with relapsing or progressive forms of MS.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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