Bioss

P2X5b Polyclonal Antibody

Name: P2X5b Polyclonal Antibody
Brand: Bioss
SKU: BS-12109R

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (2)

图: 1 / 2

P2X5b Antibody (BS-12109R) in WB

Raji (hu) lysates probed with P2X5b Polyclonal Antibody, unconjugated (bs-12109R) at 1:300 overnight at 4°C followed by a conjugated secondary antibody at 1:10000 for 60 minutes at 37°C.

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Immunogen image

Immunogen Image P2X5b Polyclonal Antibody

产品信息

BS-12109R

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:300

免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫组化（冰冻） (IHC (F))

1:100-1:500

免疫细胞化学 (ICC/IF)

1:100-1:500

酶联免疫吸附实验 (ELISA)

1:500-1:1,000

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide derived from human P2X5b, amino acids 261-360.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

内含物

0.02% ProClin 300

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both. They are characterized by intracellular amino- and carboxy-termini. P2X receptors are expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, which acts as a neurotransmitter. The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: ATP receptor; ATP receptor subunit; ionotropic ATP receptor P2X5; lymphoid-restricted histocompatibility antigen-1; P2X purinoceptor 5; P2X5; Purinergic receptor; purinergic receptor P2X, ligand gated ion channel, 5; purinergic receptor P2X, ligand-gated ion channel, 5; purinergic receptor P2X5-2

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基因别名: LRH-1; P2RX5; P2X5; P2X5FL; P2X5R

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UniProt ID: (Human) Q93086, (Mouse) Q91VE2, (Rat) P51578

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Entrez Gene ID: (Human) 5026, (Mouse) 94045, (Rat) 113995

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功能

purinergic nucleotide receptor activity transmembrane signaling receptor activity extracellular ATP-gated cation channel activity ion channel activity ATP binding GTP binding drug binding zinc ion binding ligand-gated ion channel

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