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          • Primary Antibodies ›
          • PABPC1 Antibodies

          Invitrogen

          PABPC1 Recombinant Rabbit Monoclonal Antibody (7J7M4)

          查看其他6个PABPC1抗体

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          Cite PABPC1 Recombinant Rabbit Monoclonal Antibody (7J7M4)

          Additional Information:
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          • 抗体检测数据 (7)
          PABPC1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          PABPC1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          图: 1 / 7

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          PABPC1 Antibody (MA575559) in ICC/IF

          Immunocytochemistry analysis of PABPC1 in NIH/3T3 cells. Samples were incubated with monoclonal PABPC1 (Product # MA575559) antibody at a dilution of 1:200 (red), followed by alpha Tubulin (1:400, green), and DAPI. Objective: 100x.. {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
          已发表图片由___提供 benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          查看产品

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          PABPC1 Antibody in Immunocytochemistry (ICC/IF)
          PABPC1 Antibody in Immunocytochemistry (ICC/IF)
          PABPC1 Antibody in Immunocytochemistry (ICC/IF)
          PABPC1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PABPC1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PABPC1 Antibody in Western Blot (WB)
          PABPC1 Antibody in Immunoprecipitation (IP)

          Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

          产品信息

          MA575559

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          1:1,000-1:5,000
          -

          免疫组化(石蜡) (IHC (P))

          1:100-1:500
          -

          免疫细胞化学 (ICC/IF)

          1:50-1:200
          -

          酶联免疫吸附实验 (ELISA)

          1 µg/mL
          -

          免疫沉淀 (IP)

          0.5-4 µg
          -
          产品规格

          种属反应

          Human, Mouse, Rat

          宿主/亚型

          Rabbit / IgG

          Expression System

          HEK293 cells

          分类

          Recombinant Monoclonal

          类型

          Antibody

          克隆号

          7J7M4

          抗原

          Synthetic peptide. This information is considered to be commercially sensitive.

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Liquid

          浓度

          1.55 mg/mL

          规格

          155 µg

          纯化类型

          Affinity chromatography

          保存液

          PBS, pH 7.4, with 0.05% BSA, 50% glycerol

          内含物

          0.05% ProClin 300

          保存条件

          -20°C, Avoid Freeze/Thaw Cycles

          运输条件

          Ambient (domestic); Wet ice (international)

          靶标信息

          PABPC1b encodes a poly(A) binding protein|The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs|The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay|The gene is part of a small gene family including three protein-coding genes and several pseudogenes

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

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          引用该产品

          生物信息学

          蛋白别名: ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); ADP-ribosyltransferase diphtheria toxin-like 1; ADP-ribosyltransferase NAD(+); carboxypeptidase A1 (pancreatic); casein kinase I; casein kinase I alpha S-like; CASP-1; caspase 1, apoptosis-related cysteine peptidase; CKI-alpha; CKI-alpha-like; class IVb beta tubulin; clock regulator kinase; CSNK1A1; cysteine protease; DNA ADP-ribosyltransferase PARP1; down-regulated in lung cancer; epididymis secretory sperm binding protein; epididymis secretory sperm binding protein Li 77p; G protein beta1/gamma2 subunit-interacting factor 1; H3 histone family, member A; HIST1H3A; histone 1, H3a; histone cluster 1 H3 family member a; histone cluster 1, H3a; histone H3/a; IL-1 beta-converting enzyme; IL-1B converting enzyme; IL-1BC; IL1B-convertase; interleukin 1, beta, convertase; interleukin 1-B converting enzyme; interleukin-1 beta convertase; interleukin-1 beta-converting enzyme; microtubule protein; microtubule-associated protein tau; NAD(+) ADP-ribosyltransferase 1; neurofibrillary tangle protein; p45; PABP-1; pabpc1; paired helical filament-tau; pancreatic carboxypeptidase A; PHF-tau; poly (ADP-ribose) polymerase family, member 1; poly A binding protein, cytoplasmic 1 b; poly(A) binding protein, cytoplasmic 2; poly(A)-binding protein 1; poly(ADP-ribose) polymerase; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase; poly[ADP-ribose] synthase 1; protein phosphatase 1, regulatory subunit 103; protein poly-ADP-ribosyltransferase PARP1; Tau-derived paired helical filament hexapeptide; tubulin beta-2 chain; tubulin beta-2C chain; tubulin, beta 2C; tubulin, beta, 2; unnamed protein product; zgc:77608

          查看更多 收起

          基因别名: ADPRT; ADPRT 1; ADPRT1; ARTD1; Beta2; CK1; CK1a; CKIa; CPA; DDPAC; ePAB; FTD1; FTDP-17; H3/A; H3FA; HEL-S-77p; HIST1H3A; HLCDGP1; ICE; IL1BC; LCAEOD; MAPTL; MSTD; MTBT1; MTBT2; P45; PAB1; PABP; PABP 1; PABP1; PABPC2; PabpI; PABPL1; pADPRT-1; PARP; PARP-1; PARS; Poly-PARP; PPND; PPOL; PPP1R103; PRO2975; TAU; tau-40; Tau-PHF6; TUBB2; TUBB2C

          查看更多 收起

          UniProt ID: (Human) P29466, (Human) P15085, (Human) P48729, (Human) Q8N752, (Mouse) P29452, (Rat) P97633, (Human) P68431, (Human) P10636, (Human) P11940, (Human) P09874, (Rat) Q9EPH8, (Mouse) P29341, (Human) P68371

          查看更多 收起

          Entrez Gene ID: (Human) 834, (Human) 1357, (Human) 1452, (Human) 122011, (Mouse) 12362, (Rat) 113927, (Human) 8350, (Human) 4137, (Human) 26986, (Human) 142, (Rat) 171350, (Mouse) 18458, (Human) 10383

          查看更多 收起

          功能
          endopeptidase activity cysteine-type endopeptidase activity protein binding cysteine-type peptidase activity cysteine-type endopeptidase activator activity involved in apoptotic process enzyme binding kinase binding cytokine binding identical protein binding CARD domain binding metallocarboxypeptidase activity exopeptidase activity zinc ion binding protein kinase activity protein serine/threonine kinase activity ATP binding protein serine kinase activity peptidase activity scaffold protein binding magnesium ion binding peptide binding phosphoprotein binding DNA binding structural constituent of chromatin nucleosomal DNA binding cadherin binding protein heterodimerization activity AT DNA binding double-stranded DNA binding single-stranded DNA binding RNA binding actin binding enzyme inhibitor activity microtubule binding tubulin binding SH3 domain binding protein kinase binding protein binding, bridging apolipoprotein binding dynactin binding phosphatidylinositol binding sequence-specific DNA binding chaperone binding protein phosphatase 2A binding Hsp90 protein binding lipoprotein particle binding histone-dependent DNA binding microtubule lateral binding microtubule stabilizing activity phosphatidylinositol bisphosphate binding nucleic acid binding mRNA binding mRNA 3'-UTR binding poly(A) binding poly(U) RNA binding translation activator activity chromatin binding damaged DNA binding NAD+ ADP-ribosyltransferase activity enzyme activator activity estrogen receptor binding nucleosome binding ubiquitin protein ligase binding protein homodimerization activity histone deacetylase binding non-sequence-specific DNA binding, bending NAD binding RNA polymerase II sequence-specific DNA binding transcription factor binding R-SMAD binding NAD DNA ADP-ribosyltransferase activity transcription regulator activator activity NAD+-protein-serine ADP-ribosyltransferase activity NAD+-protein-aspartate ADP-ribosyltransferase activity NAD+-protein-glutamate ADP-ribosyltransferase activity NAD+-protein-tyrosine ADP-ribosyltransferase activity NAD+-protein-histidine ADP-ribosyltransferase activity NAD+-histone H2BS6 serine ADP-ribosyltransferase activity NAD+-histone H3S10 serine ADP-ribosyltransferase activity NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity single-strand break-containing DNA binding protein ADP-ribosylase activity double-stranded RNA binding GTPase activity structural constituent of cytoskeleton GTP binding MHC class I protein binding
          参与通路
          microtubule cytoskeleton organization mitotic cell cycle cytoskeleton organization microtubule-based process sperm motility natural killer cell mediated cytotoxicity protein phosphorylation Golgi organization signal transduction cell surface receptor signaling pathway Wnt signaling pathway viral protein processing regulation of Wnt signaling pathway cellular response to nutrient positive regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of Rho protein signal transduction proteasome-mediated ubiquitin-dependent protein catabolic process intermediate filament cytoskeleton organization negative regulation of canonical Wnt signaling pathway negative regulation of NLRP3 inflammasome complex assembly positive regulation of TORC1 signaling mRNA splicing, via spliceosome gene silencing by RNA positive regulation of viral genome replication mRNA stabilization positive regulation of nuclear-transcribed mRNA poly(A) tail shortening CRD-mediated mRNA stabilization negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay positive regulation of cytoplasmic translation negative regulation of transcription from RNA polymerase II promoter response to hypoxia microglial cell activation plasma membrane repair positive regulation of cytokine production pattern recognition receptor signaling pathway proteolysis inflammatory response osmosensory signaling pathway myoblast fusion memory protein secretion response to xenobiotic stimulus response to bacterium regulation of autophagy programmed cell death protein processing protein autoprocessing protein catabolic process response to lipopolysaccharide positive regulation of interleukin-1 alpha production positive regulation of interleukin-1 beta production positive regulation of interleukin-18 production response to ATP interleukin-18-mediated signaling pathway defense response to bacterium regulation of apoptotic process positive regulation of apoptotic process positive regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of circadian sleep/wake cycle, non-REM sleep ceramide biosynthetic process regulation of inflammatory response positive regulation of inflammatory response defense response to Gram-negative bacterium protein maturation defense response to virus mitochondrial depolarization membrane hyperpolarization protein poly-ADP-ribosylation pyroptosis interleukin-1-mediated signaling pathway cellular response to lipopolysaccharide cellular response to interferon-gamma programmed necrotic cell death cytokine precursor processing signaling receptor ligand precursor processing AIM2 inflammasome complex assembly pyroptotic cell death positive regulation of NLRP3 inflammasome complex assembly response to paraquat positive regulation of tumor necrosis factor-mediated signaling pathway apoptotic process positive regulation of neuron apoptotic process icosanoid biosynthetic process cellular response to mechanical stimulus positive regulation of release of cytochrome c from mitochondria cell morphogenesis cellular response to DNA damage stimulus cell-cell signaling synapse assembly learning or memory response to lead ion negative regulation of gene expression negative regulation of mitochondrial membrane potential rRNA metabolic process axonal transport of mitochondrion central nervous system neuron development regulation of microtubule polymerization or depolymerization regulation of microtubule polymerization positive regulation of microtubule polymerization cytoplasmic microtubule organization neuron projection development positive regulation of superoxide anion generation regulation of chromosome organization stress granule assembly cellular response to heat cellular response to reactive oxygen species positive regulation of axon extension microtubule polymerization astrocyte activation regulation of synaptic plasticity intracellular distribution of mitochondria generation of neurons synapse organization regulation of calcium-mediated signaling protein polymerization protein homooligomerization regulation of microtubule-based movement axon development regulation of microtubule cytoskeleton organization plus-end-directed organelle transport along microtubule regulation of mitochondrial fission negative regulation of mitochondrial fission fibril organization axonal transport regulation of cellular response to heat regulation of long term synaptic depression positive regulation of protein localization to synapse neurofibrillary tangle assembly negative regulation of establishment of protein localization to mitochondrion positive regulation of cellular protein localization amyloid fibril formation cellular response to nerve growth factor stimulus cellular response to brain-derived neurotrophic factor stimulus single strand break repair telomere maintenance DNA repair double-strand break repair transcription from RNA polymerase II promoter mitochondrion organization transforming growth factor beta receptor signaling pathway response to gamma radiation positive regulation of cardiac muscle hypertrophy carbohydrate biosynthetic process signal transduction involved in regulation of gene expression macrophage differentiation DNA ADP-ribosylation mitochondrial DNA metabolic process positive regulation of DNA-templated transcription, elongation cellular response to insulin stimulus regulation of protein localization positive regulation of intracellular estrogen receptor signaling pathway negative regulation of transcription elongation from RNA polymerase II promoter cellular response to oxidative stress cellular response to UV protein modification process mitochondrial DNA repair regulation of circadian sleep/wake cycle, non-REM sleep response to ethanol negative regulation of innate immune response negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter decidualization positive regulation of mitochondrial depolarization positive regulation of SMAD protein import into nucleus positive regulation of necroptotic process protein auto-ADP-ribosylation protein localization to chromatin establishment of protein localization to chromatin cellular response to zinc ion cellular response to transforming growth factor beta stimulus replication fork reversal negative regulation of cGAS/STING signaling pathway positive regulation of protein localization to nucleus cellular response to oxygen-containing compound regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway response to aldosterone negative regulation of adipose tissue development negative regulation of telomere maintenance via telomere lengthening cellular response to beta-amyloid positive regulation of myofibroblast differentiation regulation of base-excision repair positive regulation of double-strand break repair via homologous recombination ATP generation from poly-ADP-D-ribose negative regulation of ATP biosynthetic process leukotriene metabolic process response to cadmium ion chromatin organization nucleosome assembly heterochromatin assembly telomere organization regulation of gene expression, epigenetic biological_process
          It has to be done as per old AB suggested Products section.

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