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Invitrogen
PACT Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-65135
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.3 mg/mL
规格
30 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: KLAKHRAAEAA INILKANASI CFAVPDPLMP DPSKQPKNQL NPIGSLQELA IHHGWRLPEY TLSQEGGPAH KREYTTICRL ESFMETGK
Highest antigen sequence identity to the following orthologs - mouse 100%, rat 100%.
靶标信息
PRKRA appears to have a pro-apoptotic function that may be suppressed in the presence of growth factor. It activates EIF2AK2 in the absence of double-stranded RNA (dsRNA).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: dsRNA-binding protein; PKR interacting protein; PKR-associated protein X; PKR-associating protein X; PRKRA; protein activator of the interferon-induced protein kinase; protein kinase, interferon-inducible double-stranded RNA-dependent activator; unnamed protein product
基因别名: DYT16; HSD14; PACT; RAX
UniProt ID: (Human) O75569
Entrez Gene ID: (Human) 8575
immune response
negative regulation of cell proliferation
response to virus
production of siRNA involved in RNA interference
pre-miRNA processing
production of miRNAs involved in gene silencing by miRNA
protein stabilization
regulation of production of small RNA involved in gene silencing by RNA
small RNA loading onto RISC
antiviral innate immune response
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