Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
PAICS Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
12967-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PAICS Fusion Protein Ag3621 (76-425 aa encoded by BC010273)
偶联物
形式
Liquid
浓度
0.17 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: AFTRKCGET AFIAPQCEMI PIEWVCRRIA TGSFLKRNPG VKEGYKFYPP KVELFFKDDA NNDPQWSEEQ LIAAKFCFAG LLIGQTEVDI MSHATQAIFE ILEKSWLPQN CTLVDMKIEF GVDVTTKEIV LADVIDNDSW RLWPSGDRSQ QKDKQSYRDL KEVTPEGLQM VKKNFEWVAE RVELLLKSES QCRVVVLMGS TSDLGHCEKI KKACGNFGIP CELRVTSAHK GPDETLRIKA EYEGDGIPTV FVAVAGRSNG LGPVMSGNTA YPVISCPPLT PDWGVQDVWS SLRLPSGLGC STVLSPEGSA QFAAQIFGLS NHLVWSKLRA SILNTWISLK QADKKIRECN L (76-425 aa encoded by BC010273)
靶标信息
This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: AIR carboxylase; Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase; multifunctional protein ADE2; multifunctional protein ADE2H1; PAICS; phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase; SAICAR synthetase
基因别名: 2610511I09Rik; ADE2; ADE2H1; AIRC; PAICS; PAIS
UniProt ID: (Human) P22234, (Mouse) Q9DCL9
Entrez Gene ID: (Human) 10606, (Mouse) 67054
phosphoribosylaminoimidazole carboxylase activity
phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
protein binding
ATP binding
identical protein binding
cadherin binding involved in cell-cell adhesion
nucleotide binding
catalytic activity
lyase activity
carboxy-lyase activity
ligase activity
