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Proteintech
PAPPA Polyclonal Antibody
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产品信息
18095-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PAPPA fusion protein Ag11863
偶联物
形式
Liquid
浓度
0.55 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: ACEPVDCSIP DHHQVYAASF SCPEGTTFGS QCSFQCRHPA QLKGNNSLLT CMEDGLWSFP EALCELMCLA PPPVPNADLQ TARCRENKHK VGSFCKYKCK PGYHVPGSSR KSKKRAFKTQ CTQDGSWQEG ACVPVTCDPP PPKFHGLYQC TNGFQFNSEC RIKCEDSDAS QGLGSNVIHC RKDGTWNGSF HVCQEMQGQC SVPNELNSNL KLQCPDGYAI GSECATSCLD HNSESIILPM NVTVRDIPHW LNPTRVERVV CTAGLKWYPH PALIHCVKGC EPFMGDNYCD AINNRAFCNY DGGDCCTSTV KTKKVTPFPM SCDLQGDCAC RDPQAQEHSR KDLQGYSHG
靶标信息
Pregnancy-associated plasma protein-A (PAPP-A, Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) is a large heterottetrameric glycoprotein of approximately 500 kDa, which was first discovered in serum from pregnant women. The hetreotetramer consists of two PAPP-A subunits and two proMBP subunits. Low maternal serum levels of PAPP-A in first trimester biochemical screening is used as a marker of Down's syndrome (trisomy 21).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: aspecific BCL2 ARE-binding protein 2; differentially placenta 1 expressed protein; IGF-dependent IGFBP-4 protease; IGFBP-4 ase; insulin-like growth factor-dependent IGF binding protein-4 protease; Insulin-like growth factor-dependent IGF-binding protein 4 protease; PAPP A; PAPP-A; Pappalysin; Pappalysin-1; pregnacy-associated plasma protein A; Pregnancy-associated plasma protein A; pregnancy-associated plasma protein A, pappalysin 1; RP11-45A16.1
基因别名: ASBABP2; DIPLA1; IGFBP-4ase; PAPA; PAPP-A; PAPPA; PAPPA1
UniProt ID: (Human) Q08371
Entrez Gene ID: (Human) 5069
