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Invitrogen
PAPPA Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-79782
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived human PAPP A recombinant protein (Position: R95-Q388).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
500 µg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Human Placenta Tissue, HT1080 whole cell, SKOV whole cell, 22RV1 whole cell, SW620 whole cell, MM231 whole cell. IHC: Human Placenta Tissue.
靶标信息
Pregnancy-associated plasma protein-A (PAPP-A, Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) is a large heterottetrameric glycoprotein of approximately 500 kDa, which was first discovered in serum from pregnant women. The hetreotetramer consists of two PAPP-A subunits and two proMBP subunits. Low maternal serum levels of PAPP-A in first trimester biochemical screening is used as a marker of Down's syndrome (trisomy 21).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: IGF-dependent IGFBP-4 protease; IGFBP-4 ase; Insulin-like growth factor-dependent IGF-binding protein 4 protease; PAPP A; PAPP-A; Pappalysin; Pappalysin-1; Pregnancy-associated plasma protein A; RP11-45A16.1
基因别名: PAPPA
Entrez Gene ID: (Human) 5069
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