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Invitrogen
PARP14 Recombinant Rabbit Monoclonal Antibody (HL1180)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-46949
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
HL1180
抗原
Recombinant protein encompassing a sequence within the C-terminus region of human PARP14. The exact sequence is proprietary.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Store as concentrated solution.
Centrifuge briefly prior to opening vial.
靶标信息
Poly [ADP-ribose] polymerase 14 (PARP14) is a B aggressive lymphoma protein belonging to the PARP protein family. Poly ADP ribosylation is a DNA damage dependent post translational modification of histones and other nuclear proteins that mediates DNA repair. PARP proteins with a macrodomain are also involved in gene expression through transcriptional regulation. PARP14 controls STAT6 dependent transcription by enhancing binding to the promoter in the presence of a positive signal (i.e. IL4 stimulation).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ADP-ribosyltransferase diphtheria toxin-like 8; b aggressive lymphoma protein 2; B-aggressive lymphoma 2; collaborator of STAT6; PARP-14; poly [ADP-ribose] polymerase 14; transcription cofactor; unnamed protein product
基因别名: 1600029O10Rik; ARTD8; BAL2; CoaSt6; mKIAA1268; PARP-14; pART8; RGD1310490
UniProt ID: (Human) Q460N5, (Mouse) Q2EMV9
Entrez Gene ID: (Human) 54625, (Rat) 303903, (Mouse) 547253
negative regulation of gene expression
NAD catabolic process
positive regulation of tyrosine phosphorylation of STAT protein
negative regulation of tyrosine phosphorylation of STAT protein
negative regulation of transcription, DNA-templated
negative regulation of interferon-gamma-mediated signaling pathway
protein poly-ADP-ribosylation
positive regulation of interleukin-4-mediated signaling pathway
positive regulation of cytokine-mediated signaling pathway
biological_process
regulation of interferon-gamma-mediated signaling pathway
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
