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Proteintech
PAX7 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
20570-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.45 mg/mL
规格
67.5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
The antibody is specific to PAX7. It will not cross react with other PAX members.
靶标信息
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: FLJ37460; paired box gene 7; paired box homeotic gene 7; paired box transcription factor PAX7; paired domain gene 7; PAX7 transcriptional factor; PAX7A; PAX7B
基因别名: CMYO19; CMYP19; HUP1; MYOSCO; Pax-7; PAX7B; RMS2
UniProt ID: (Human) P23759, (Mouse) P47239
Entrez Gene ID: (Human) 5081, (Mouse) 18509
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
chromatin remodeling
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
nervous system development
skeletal muscle tissue development
positive regulation of cell proliferation
organ morphogenesis
regulation of cell fate commitment
regulation of gene expression
skeletal muscle satellite cell commitment
skeletal muscle satellite cell differentiation
spinal cord association neuron differentiation
dorsal/ventral neural tube patterning
neural tube development
skeletal muscle tissue regeneration
positive regulation of transcription from RNA polymerase II promoter
neuron fate commitment
embryonic skeletal system development
tissue morphogenesis
cartilage development
muscle tissue morphogenesis
skeletal muscle organ development
regulation of chromatin organization
positive regulation of myoblast proliferation
anatomical structure morphogenesis
negative regulation of apoptotic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
