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Abnova
PCMT1 Monoclonal Antibody (1D6)
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产品信息
H00005110-M02
产品规格
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
1D6
抗原
PCMT1 (NP_005380, 117 a.a. approximately 225 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
See Label
规格
100 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: DDSVNNVRKD DPTLLSSGRV QLVVGDGRMG YAEEAPYDAI HVGAAAPVVP QALIDQLKPG GRLILPVGPA GGNQMLEQYD KLQDGSIKMK PLMGVIYVPL TDKEKQWSR
靶标信息
Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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