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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total PTPRR.
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domains, and thus represents a receptor-type PTP. The similar gene predominately expressed in mouse brain was found to associate with, and thus regulate the activity and cellular localization of MAP kinases. The rat counterpart of this gene was reported to be regulated by the nerve growth factor, which suggested the function of this gene in neuronal growth and differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Ch-1 PTPase; ch-1PTPase; ECPPT; NC-PTPCOM1; phosphotyrosine phosphatase 13; protein tyrosine phosphatase Cr1PTPase; protein-tyrosine phosphatase NC-PTPCOM1; protein-tyrosine phosphatase PCPTP1; protein-tyrosine-phosphatase-SL; PTPPBS gamma; R-PTP-R; STEP-like PTPase; tyrosine phosphatase CBPTP; unnamed protein product
基因别名: EC-PTP; Gmcp1; mPTP213; PC12-PTP1; PCPTP1; PTP-SL; PTPBR7; PTPRQ; R-PTP-R; RPTPRR
UniProt ID: (Human) Q15256, (Rat) O08617, (Mouse) Q62132
Entrez Gene ID: (Human) 5801, (Rat) 94202, (Mouse) 19279