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Invitrogen
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PA1-31125 detects PDE1B from mouse, rat, human samples.
PA1-31125 has been successfully used in immunocytochemistry, immunoprecipitation, Western blot applications.
The PA1-31125 immunogen is: Synthetic peptides (N terminal).
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。