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Proteintech
PDE1C Polyclonal Antibody
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产品信息
13785-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PDE1C Fusion Protein Ag4798 (284-634 aa encoded by BC022525)
偶联物
形式
Liquid
浓度
0.21 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: RSDPAILYN DRSVLENHHL SAAYRLLQDD EEMNILINLS KDDWREFRTL VIEMVMATDM SCHFQQIKAM KTALQQPEAI EKPKALSLML HTADISHPAK AWDLHHRWTM SLLEEFFRQG DREAELGLPF SPLCDRKSTM VAQSQVGFID FIVEPTFTVL TDMTEKIVSP LIDETSQTGG TGQRRSSLNS ISSSDAKRSG VKTSGSEGSA PINNSVISVD YKSFKATWTE VVHINRERWR AKVPKEEKAK KEAEEKARMA AEEQQKEMEA KSQAEEGASG KAEKKTSGET KNQVNGTRAN KSDNPRGKNS KAEKSSGEQQ QNGDFKDGKN KTDKKDHSNI GNDSKKTDDS QE (284-634 aa encoded by BC022525)
靶标信息
Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin -dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 ).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C; Cam-PDE 1C; cyclic nucleotide phosphodiesterase 1 C; Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C; Hcam3; Human 3',5' cyclic nucleotide phosphodiesterase (HSPDE1C1A); phosphodiesterase 1C calmodulin-dependent (70kD); phosphodiesterase 1C, calmodulin-dependent 70kDa
基因别名: cam-PDE 1C; hCam-3; Hcam3; PDE1C; Pde1c2
UniProt ID: (Human) Q14123, (Mouse) Q64338, (Rat) Q63421
Entrez Gene ID: (Human) 5137, (Mouse) 18575, (Rat) 81742
calmodulin-dependent cyclic-nucleotide phosphodiesterase activity
calmodulin binding
metal ion binding
3',5'-cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-AMP phosphodiesterase activity
phosphoric diester hydrolase activity
hydrolase activity
cAMP binding
calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity
phosphodiesterase
