Proteintech

PDGFD Polyclonal Antibody

Name: PDGFD Polyclonal Antibody
Brand: Proteintech
SKU: 14075-1-AP

7 篇参考文献

查看其他6个PDGF-D抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (4)

PDGFD Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 4

PDGFD Antibody (14075-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human prostate cancer using 14075-1-AP (PDGFD antibody) at dilution of 1:50 (under 40x lens).

PDGFD Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

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Immunogen image

Immunogen Image PDGFD Polyclonal Antibody

产品信息

14075-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

Assay-dependent

查看3篇已发表文章 3篇已发表文章

免疫组化 (IHC)

查看3篇已发表文章 3篇已发表文章

免疫组化（石蜡） (IHC (P))

1:20-1:200

免疫组织化学（多聚甲醛固定） (IHC (PFA))

1:50

免疫细胞化学 (ICC/IF)

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Goat, Human, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

PDGFD Fusion Protein Ag5154 (1-364 aa encoded by BC030645)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.3 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: MHRLIFVYT LICANFCSCR DTSATPQSAS IKALRNANLR RDDLYRRDET IQVKGNGYVQ SPRFPNSYPR NLLLTWRLHS QENTRIQLVF DNQFGLEEAE NDICRYDFVE VEDISETSTI IRGRWCGHKE VPPRIKSRTN QIKITFKSDD YFVAKPGFKI YYSLLEDFQP AAASETNWES VTSSISGVSY NSPSVTDPTL IADALDKKIA EFDTVEDLLK YFNPESWQED LENMYLDTPR YRGRSYHDRK SKVDLDRLND DAKRYSCTPR NYSVNIREEL KLANVVFFPR CLLVQRCGGN CGCGTVNWRS CTCNSGKTVK KYHEVLQFEP GHIKRRGRAK TMALVDIQLD HHERCDCICS SRPPR (1-364 aa encoded by BC030645)

靶标信息

The platelet-derived growth factor (PDGF) family consists of four members; PDGF-A, PDGF-B, PDGF-C and PDGF-D (spinal cord-derived growth factor-B or iris-expressed growth factor). PDGF members form disulphide-bonded dimeric isoforms, which are important for growth, survival and function in several types of connective tissue cells. Their biological effects are mediated via two tyrosine kinase receptors, PDGFR-a and PDGFR-b, and PDGF-mediated signaling is critical for development of many organ systems. PDGF-D has a two-domain structure similar to PDGF-C and is secreted as a disulphide-linked homodimer, PDGF-DD. PDGF-D induces cellular transformation and promotes tumor growth by accelerating the proliferation rate of tumor cells and by stimulation of tumor neovascularization. PDGF-D may play a role in the development of brain tumors. The potential oncogenic activity of PDGF-DD may be important for the development and/or progression of prostate cancer. PDGF-D is expressed in fibroblastic adventitial cells, cultured endothelial cells and in a variety of tumor cell lines including those derived from ovarian, renal and lung cancers, as well as from astrocytomas and medulloblastomas. PDGF-D is expressed in the human kidney.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: Iris-expressed growth factor; PDGF-D; Platelet-derived growth factor D; platelet-derived growth factor, D polypeptide; SCDGF-B; spinal cord derived growth factor B; Spinal cord-derived growth factor B; spinal cord-derived growth factor-B; spinal-cord derived growth factor-B protein

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基因别名: 1110003I09Rik; IEGF; MSTP036; PDGFD; rSCDGF-B; SCDGF-B; SCDGFB; UNQ1899/PRO4345

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UniProt ID: (Human) Q9GZP0, (Rat) Q9EQT1, (Mouse) Q925I7

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Entrez Gene ID: (Human) 80310, (Rat) 66018, (Mouse) 71785

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功能

platelet-derived growth factor receptor binding growth factor activity growth factor

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