Search
Invitrogen
PDGFRA Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
产品信息
PA5149843
产品规格
种属反应
Bovine,
Dog,
Guinea pig,
Goat,
Human,
Mouse,
Sheep,
Pig,
Rat
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
Recombinant Platelet Derived Growth Factor Receptor Alpha (PDGFRa) (Ala170-Glu387)
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Alpha platelet-derived growth factor receptor; Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha); Alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140a; CD140a antigen; MGC74795; OTTHUMP00000218656; PDGF A-chain; PDGF alpha chain; PDGF Receptor alpha; PDGF subunit A; PDGF-1; PDGF-R-alpha; PDGFR-2; pdgfr-a; PDGFR-alpha; Platelet-derived growth factor alpha receptor; Platelet-derived growth factor receptor 2; Platelet-derived growth factor receptor alpha; platelet-derived growth factor receptor, alpha polypeptide; unnamed protein product
基因别名: AI115593; APDGFR; CD140A; PDGFACE; PDGFR-2; PDGFR2; PDGFRA; RHEPDGFRA
UniProt ID: (Human) P16234, (Rat) P20786, (Mouse) P26618
nucleotide binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
platelet-derived growth factor alpha-receptor activity
vascular endothelial growth factor-activated receptor activity
platelet-derived growth factor receptor binding
protein binding
ATP binding
kinase activity
transferase activity
vascular endothelial growth factor binding
protein homodimerization activity
macromolecular complex binding
platelet-derived growth factor binding
phospholipase C activator activity
protein complex binding
phosphatidylinositol 3-kinase binding
protein dimerization activity
transferase activity, transferring phosphorus-containing groups
transmembrane signal receptor
luteinization
in utero embryonic development
cell activation
hematopoietic progenitor cell differentiation
chemotaxis
transmembrane receptor protein tyrosine kinase signaling pathway
estrogen metabolic process
positive regulation of cell proliferation
female gonad development
anatomical structure morphogenesis
organ morphogenesis
negative regulation of platelet activation
cell migration
peptidyl-tyrosine phosphorylation
signal transduction involved in regulation of gene expression
extracellular matrix organization
lung development
adrenal gland development
positive regulation of cell migration
male genitalia development
regulation of actin cytoskeleton organization
Leydig cell differentiation
cellular response to reactive oxygen species
platelet-derived growth factor receptor-alpha signaling pathway
positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway
wound healing
odontogenesis of dentin-containing tooth
protein autophosphorylation
platelet-derived growth factor receptor signaling pathway
positive regulation of fibroblast proliferation
embryonic digestive tract morphogenesis
embryonic cranial skeleton morphogenesis
embryonic skeletal system morphogenesis
skeletal system morphogenesis
positive regulation of calcium-mediated signaling
white fat cell differentiation
positive regulation of chemotaxis
positive regulation of protein kinase B signaling
cardiac myofibril assembly
palate development
face morphogenesis
cell chemotaxis
retina vasculature development in camera-type eye
positive regulation of ERK1 and ERK2 cascade
platelet aggregation
cellular response to amino acid stimulus
metanephric glomerular capillary formation
regulation of mesenchymal stem cell differentiation
positive regulation of cytosolic calcium ion concentration
response to hormone
response to organic substance
response to inorganic substance
positive regulation of phospholipase C activity
response to estradiol
response to cytokine
cellular response to platelet-derived growth factor stimulus
vascular endothelial growth factor signaling pathway
gliogenesis
positive regulation of phosphatidylinositol 3-kinase activity
response to estrogen
positive regulation of DNA replication
phosphatidylinositol-mediated signaling
inner ear development
regulation of chemotaxis
response to hyperoxia
protein phosphorylation
multicellular organism development
phosphorylation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
