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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: MKVWLLLGL LLVHEALEDV TGQHLPKNKR PKEPGENRIK PTNKKVKPKI PKMKDRDSAN SAPKTQSIMM QVLDKGRFQK PAATLSLLAG QTVELRCKGS RIGWSYPAYL DTFKDSRLSV KQNERYGQLT LVNSTSADTG EFSCWVQLCS GYICRKDEAK TGSTYIFFTE KGELFVPSPS YFDVVYLNPD RQAVVPCRVT VLSAKVTLHR EFPAKEIPAN GTDIVYDMKR GFVYLQPHSE HQGVVYCRAE AGGRSQISVK YQLLYVAVPS GPPSTTILAS SNKVKSGDDI SVLCTVLGEP DVEVEFTWIF PGQKDERPVT IQDTWRLIHR GLGHTTRISQ SVITVEDFET IDAGYYICTA QNLQGQTTVA TTVEFS (1-375 aa encoded by B C010927)
PDGFRL bears significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in the PDGFRL gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests PDGFRL may function as a tumor suppressor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: PDGF receptor beta-like tumor suppressor; PDGFR-like protein; PDGFRL; platelet-derived growth factor-beta-like tumor suppressor; unnamed protein product
基因别名: 1110039P19Rik; PDGRL; PRLTS
UniProt ID: (Human) Q15198, (Rat) Q5RJP7, (Mouse) Q6PE55
Entrez Gene ID: (Human) 5157, (Rat) 290771, (Mouse) 68797