Invitrogen

PEX5L Polyclonal Antibody

Name: PEX5L Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-63510

高级验证

查看其他29个PEX5L抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (4)
高级验证 (1)

PEX5L Antibody in Immunohistochemistry (IHC)

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PEX5L Antibody (PA5-63510) in IHC

Immunohistochemical staining of PEX5L in human cerebral cortex and liver tissues using PEX5L Polyclonal Antibody (Product # PA5-63510). Corresponding PEX5L RNA-seq data are presented for the same tissues.

Product Image Gallery

PEX5L Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of PEX5L demonstrates antibody specificity. Immunohistochemical analysis of PEX5L using anti-PEX5L Polyclonal Antibody (Product # PA5-63510), shows significant staining of PEX5L in human cerebral cortex and shows minimal or weak staining in human liver tissues. The relative expression levels of PEX5L within each tissue is shown using RNA-Seq. {RE}

Immunogen image

Immunogen Image PEX5L Polyclonal Antibody

产品信息

PA5-63510

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:500-1:1,000

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human PEX5L. Recombinant protein control fragment (Product #RP-103316).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.05 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2645413

产品详细信息

Immunogen sequence: PVTSNTAVLT TGLDLLDLSE PVSQTQTKAK KSEPSSKTSS LKKKADGSDL ISTDAEQRGQ PLRVPETSSL DLDIQTQLEK WDDVKFHGDR NTKG

Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 91%.

靶标信息

Pex5l is an accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence. Research studies have shown that Pex5l is expressed in the brain, testis and pancreas. Diseases associated with PEX5L include Rhizomelic Chondrodysplasia Punctata, Type 5 and Rhizomelic Chondrodysplasia Punctata, Type 2.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: HCN channel auxiliary subunit; Peroxin-5-related protein; peroxisomal biogenesis factor 5-like; Peroxisome biogenesis factor 5-like; PEX2-related protein; PEX5-like protein; PEX5-related protein; Pex5p-related protein; Pex5Rp; Tetratricopeptide repeat-containing Rab8b-interacting protein

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基因别名: PEX5L; PEX5R; PEX5RP; PXR2; PXR2B; TRIP8b

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UniProt ID: (Human) Q8IYB4

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Entrez Gene ID: (Human) 51555

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功能

peroxisome targeting sequence binding small GTPase binding membrane trafficking regulatory protein

参与通路

protein import into peroxisome matrix, docking regulation of cAMP-mediated signaling